Evaluation of Renal Function By Cystatin C in Renal Transplant Recipients

Ayub, Salma; Zafar, Mirza Naqi; Aziz, Tahir; Iqbal, Tanweer; Khan, Sadia; Rizvi, Syed Adibul Hasan

doi:10.6002/ect.2013.0202

Cited by 7 publications

(4 citation statements)

References 21 publications

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“…The contemporary literature reports that there is a gradual shift towards older age groups among renal transplant recipients as well donors in the developed world 13 but local data shows that most of the renal transplant recipients are from the age groups between 30-35 years so our findings are similar to what has been reported previously from the developing regions of the world. [14][15][16][17] Majority of the renal transplant recipients (82.1%) were male in this study while 59.0% live kidney donors were females. Data from the developed countries like USA and UK reports male gender to have predominance among cases undergoing renal transplant or hemodialysis.…”

Section: Discussionmentioning

confidence: 99%

Medical complications after live donor kidney transplantation: An experience from tertiary care hospital of south Punjab, Pakistan.

Khan

Malik

Manzoor

et al. 2023

TPMJ

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Objective: To determine the frequency of medical complications after renal transplantation in recipients. Study Design: Prospective Cohort study. Setting: Nephrology Unit, Bahawal Victoria Hospital, Bahawalpur. Period: December 2018 to March 2022. Material & Methods: All patients undergoing renal transplant during the study period were included. Patients unwilling to be part of this study or losing follow-ups were excluded. At the time of enrollment, all patients underwent pre-transplant work-up and routine investigations. Baseline characteristics of renal transplant recipients and donors were noted while frequency of post renal transplant medical complications was also noted. Results: In a total of 39 renal transplant recipients, 32 (82.1%) were male while the mean age was 30.31±7.21 years. Mean duration of dialysis before transplantation was 6.81±5.15 months (ranging between 0-24 months). Mean age of the live donors was 35.90±9.36 years. Mean duration of follow up was 26.15±11.62 months. Renal graft dysfunction was reported in 10 (25.6%) patients. Most common medical complications reported in post-transplantation period were sepsis 19 (48.7%), anemia 19(48.7%), secondary polycythemia 10 (25.6%), CMV infection 4 (10.3%) and new onset diabetes mellitus 3 (7.7%). Mortality was reported in 2 (5.1%) renal transplant recipients and the cause of mortality in both those patients was sepsis. Conclusion: Medical complications are common after renal transplantation. Sepsis being more common in 1st6-months post-transplant period. Early recognition and management of these complications is essential for decreasing mortality and morbidity of patients.

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Section: Discussionmentioning

confidence: 99%

Medical complications after live donor kidney transplantation: An experience from tertiary care hospital of south Punjab, Pakistan.

Khan

Malik

Manzoor

et al. 2023

TPMJ

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“…Our results suggest that serum cystatin C level correlates well with serum creatinine which is similar to the observations made by Ayub et al ., Pöge et al ., and Dharnidharka et al . [ 16 17 18 ] In a recently published study that aimed to evaluate the efficacy of serum cystatin C as a marker of renal dysfunction among different CKD and postrenal transplant patients, the findings showed that serum cystatin C is negatively correlated with measured GFR in all groups. [ 19 ] In this study, we found that serum cystatin C is a better parameter than serum creatinine to diagnose renal dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Assessment of renal function using cystatin C and creatinine in Saudi patients after transplantation

Jeraiby

2021

Ann Afr Med

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“…La mediana de tasa de filtración glomerular (Crockoft-Gault) al año de trasplante fue similar a la reportada en otros estudios 14 .…”

Section: Discussionunclassified

Analysis of graftpost- transplant renal survival

Dávila¹,

Luna²,

Rey³

2015

Rev. Colomb. Nefrol.

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ResumenIntroducción: Los pacientes post trasplante renal presentan una Supervivencia media inferior a la de población general, esta supervivencia se disminuye más cuando está relacionada con pérdida del injerto; se pretende identificar la contribución de los factores de riesgo con la pérdida del injerto. Materiales y métodos:Estudio de Cohorte retrospectiva post-trasplante renal; se describieron las características generales de los pacientes; se calculó el RR (Riesgo relativo) para el riesgo de pérdida del injerto (p<0,05) y se exploraron diferencias de supervivencia en diagramas de Kapplan Meier.Resultados: Se analizaron 164 casos; la mediana de edad fue de 48 años; de peso fue 68 kg, de depuración de creatinina al año del trasplante de 57,17 mg/dl; la supervivencia global del injerto a 5 años fue del 88,4% y la de los pacientes del 92,1%.El Riesgo relativo (RR) de pérdida del injerto en quienes presentaron rechazo en el primer año fue de 3,86; (p = 0,002).Se encontraron diferencias significativas en la supervivencia del injerto a cinco años en pacientes mayores vs menores de cincuenta años de edad (96,8 vs 83,2 % respectivamente), la amplitud de estas diferencias se igualó posterior a los 70 meses (5,8 años).Conclusiones: Se identificó la contribución de los factores de riesgo pretrasplante con la pérdida del injerto; encontrando a la edad como el único factor relacionado; siendo esta menor en mayores de 50 años.Según los resultados, se sugiererealizar seguimientos más estrechosa los menores de 50 años hasta el quinto año del trasplante.Palabras clave: Supervivencia libre de enfermedad, Rechazo del injerto / epidemiología, Rechazo de Injerto, Estadísticas de Atención Médica (fuente DeCS). Analysis of graftpost-transplant renal survival AbstractIntroduction:post renal transplant patients have a lower than average survival general population, this survival is decreased more when related to graft failure; It aims to identify the contribution of risk factors with graft loss.

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Evaluation of Renal Function By Cystatin C in Renal Transplant Recipients

Cited by 7 publications

References 21 publications

Medical complications after live donor kidney transplantation: An experience from tertiary care hospital of south Punjab, Pakistan.

Medical complications after live donor kidney transplantation: An experience from tertiary care hospital of south Punjab, Pakistan.

Assessment of renal function using cystatin C and creatinine in Saudi patients after transplantation

Analysis of graftpost- transplant renal survival

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