Evaluation of Platelet Parameters in Patients With Pulmonary Hydatid Cyst

Abstract

Background:Echinococcosis is a near-cosmopolitan zoonosis caused by adult or larval stages of tapeworms (cestodes) into the genus Echinococcus (family Taeniidae). It was demonstrated that platelets were capable of killing parasites independent from leukocytes. Purpose: The aim of our study was to examine mean platelet volume (MPV), platelet mass (PM) and platelet count (PC), which are practical indicators of platelet activity in preoperative and postoperative periods of the patients with hydatid cyst.Methods:In this retrospective study we evaluated 72 patients admitted to clinic of chest surgery with a diagnosis of pulmonary hydatid cyst in our hospital between January, 2006, and October, 2008. The MPV, PC, and PM were evaluated by complete blood count. PM was calculated by multiplying MPV and PLT.Results:Preoperative MPV values of the patients was found to be significantly higher than postoperative MPV values (mean: 8.07±0.83, 7.78±0.87, p= 0.002). Preoperative PM values (median: 2456.75, range: 1013.70–5046.60) was found to be higher when compared to postoperative PM values (median: 2280.80, range: 134.20–4042.60) (p= 0.039). PC values were not significantly different between two periods (Preoperative-postoperative PC mean values: 320.48±98.42, 307.29±96.45, p= 0.286).Conclusion:In this study, we demonstrated that there were no statistical difference in PC for both periods but, MPV and PM were found statistical higher than postoperative period in preoperative period. PM and PM can be used as markers of disease activity in patients who undergo surgical resection of hydatid cyst.

The Impact of Acute Brucellosis on Mean Platelet Volume and Red Blood Cell Distribution

“…The current study results on MPV were in disagreement with the results of these two studies. Although most studies in the literature reported MPV as an inflammatory marker in many infectious and rheumatological diseases as well as a guiding parameter in diagnosis and treatment ( 7 , 8 , 19 , 25 - 27 , 30 , 32 , 33 ), the present study determined that it is not a significant inflammatory marker for brucellosis patients.…”

“…( 4 , 28 , 29 ). High MPV levels also occur in infectious diseases like pulmonary tuberculosis, CCHF, and hydatid cyst disease ( 30 - 32 ). On the other hand, lower MPV levels were detected by some researchers in active inflammatory bowel disease, rheumatic arthritis, ankylosing spondylitis, acute pancreatitis, and appendicitis ( 7 , 8 , 25 , 33 ).…”

A review of the association of mean platelet volume and red cell distribution width in inflammation

“…35 Another report has been suggested their findings. 36 MPV has been reported to be increased in infectious conditions; such as chronic prostatitis, 6 hepatic 5 and pulmonary 37 hydatid cyst disease.…”

Platelet Parameters in Hepatic Hydatid Cysts

“…Similarly, Fajardo and Rao [6] detected an increase in thrombocyte size in patients with malaria in their study. Recently, Küçükbayrak et al [7] observed preoperative and postoperative MPV values of patients with pulmonary hydatid cysts and found that MPV values were significantly increased in preoperative period compared to postoperative period. Our results were in accordance with the literature.…”