Evaluation Of <i>In-Vitro</i> Antimicrobial Activities And Phytochemical Constituents Of <i>Cassia occidentalis </i>

Abstract

The research was carried out to evaluate the in-vitro antimicrobial activity and phytochemical constituents of Cassia occ dential s. Cassia leaves were collected from Kacha town in Niger State and extracted using methano , hexane, chloroform and water extraction methods. Serial concentrations: 50 60, 70, 80, 90 and 100 % methanol, hexane, chloroform and aqueous extracts were prepared and sterilized. The bacterial isolates used; E. coli, P. multocida, S. typhi, S. typhimurium, S. pyogenes, S. pneumoniae and K. pneumoniae were authenticated using biochemical and serological methods. The suspens on (0.5) of each bacterial isolate was prepared in isotonic sodium chloride. The disc agar diffusion method was performed on 70 Mueller-Hinton agar p ates, 10 per microorganism , using serial diffusion concentrat on: 500, 600, 700, 800, 900 and 1000 mg o hexane, methanol, chloroform and water. The results showed that all the extracts of Cassia occidentalis have antimicrobial activity on E col at concentrations between 900-1000 mg. E. coli was most susceptible to hexane extract at concentration ranges between 500-1000 mg, there was no antimicrobial activity exhibited against the other tested microorganisms Phytochemical analyses showed the presence of alkaloid, tannin, saponin, glycoside and flavonoid, steroid was absent.

Synthesis and Catalytic and Biological Activities of Silver and Copper Nanoparticles Using Cassia occidentalis

“…It is used against fever, menstrual problems, and tuberculosis, as diuretic, in anaemia, in liver complaints, and as a tonic against general weakness and illness [7]. C. occidentalis leaf extracts exhibit antibacterial, antimalarial, anticarcinogenic, and hepatoprotective activity [8–10]. Chemical constituents isolated from C. occidentalis include sennoside, anthraquinone glycoside, fatty oils, flavonoid glycosides, galactomannan, polysaccharides, and tannins [11, 12].…”

ISSR marker‐based detection of genomic stability in Cassia occidentalis L. plantlets derived from somatic embryogenesis

“…An infusion of the bark is given in diabetes . Leaf extracts have antibacterial , antimalarial , antimutagenic , antiplasmodial , anticarcinogenic , analgesic, and antipyretic activities. The various medicinal implication have been mainly attributed to the presence of achrosin, aloe‐emodin, emodin, anthraquinones, anthrones, apigenin, aurantiobtusin, campesterol, cassiollin, chryso‐obtusin, chrysophanic acid, chrysarobin, chrysophanol, chrysoeriol, etc.…”

Identification of seeds based on molecular markers and secondary metabolites in Senna obtusifolia and Senna occidentalis

“…Among the adulterants, the most common and indistinguishable one is the seeds of Senna occidentalis L., which is an ayurvedic medicinal herb also belong to genus Senna Leguminosae family. Several investigations had demonstrated that S. occidentalis have antibacterial (Jafri et al 1999 ; Saganuwan and Gulumbe 2006 ), antimutagenic (Jafri et al 1999 ), antiplasmodial (Tona et al 2004 ) and hepatoprotective activities (Yadav et al 2010 ).…”