Evaluation of intraocular lens mechanical stability

Lane, Stephen S.; Collins, Stephen P.; Das, Kamal; Maass, Sean; Thatthamla, Israwal; Schatz, Hillary; Noy, Stephen Van; Jain, Rakhi

doi:10.1016/j.jcrs.2018.10.043

Cited by 33 publications

(38 citation statements)

References 13 publications

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“…In laboratory studies this lens has been shown to produce low levels of surface haze, roughness and light scatter, minimal glistenings and little axial displacement when compared to other hydrophobic acrylic IOLs. [24][25][26] Whilst these results are encouraging, there are no published clinical studies at this time. The aim of this randomized controlled trial was to evaluate visual performance, refractive outcomes, patient satisfaction and glistenings occurrence at 12 months following implantation of the Clareon® IOL compared to the Tecnis PCB00® (Johnson & Johnson Inc.), which has a low rate of reported glistenings.…”

Section: Introductionmentioning

confidence: 98%

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Stanojcic

O’Brart

Hull

et al. 2020

J Cataract Refract Surg

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Section: Introductionmentioning

confidence: 98%

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Stanojcic

O’Brart

Hull

et al. 2020

J Cataract Refract Surg

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“…Also, the differences in polychromatic image quality generated by altering IOL Abbe number are likely to be much smaller than those generated by other defocus sources. For example, recent data indicate that about 28% of pseudophakic eyes experience a residual spherical refractive error >0.5D, 36 which has been attributed to challenges of estimating post-op anterior chamber depth 37 and post-operative IOL axial instabilities, 38 which can vary with both IOL design 39 and surgical procedure. 38 Unlike the absence of a measurable visual impact of changing IOL Abbe number, 15,40 the larger spherical refractive errors attributable IOL axial power and position errors produce significant reductions in visual acuity.…”

Section: Discussionmentioning

confidence: 99%

<p>The Impact of IOL Abbe Number on Polychromatic Image Quality of Pseudophakic Eyes</p>

Bradley

Wang³

et al. 2020

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The human eye exhibits large amounts (2.5 diopters) of longitudinal chromatic aberration (LCA). Its impact on polychromatic image quality, however, has been shown experimentally and by computer modeling to be small or absent. We hypothesized that modest changes in pseudophakic LCA created by higher and lower Abbe number materials will have little or no impact on polychromatic image quality in pseudophakic eyes. Materials and Methods: Using published chromatic and monochromatic aberration data from pseudophakic eyes and higher and lower Abbe number materials (37 and 55), we computed monochromatic point spread functions for 21 wavelengths across the visible spectrum. After weighting by either the RGB spectra of a liquid crystal display or by a flat white spectrum, they were weighted by the human spectral sensitivity function (V λ) before being added to generate polychromatic PSFs. Results: In the absence of monochromatic aberrations, the reduced LCA due to higher Abbe number intraocular lens (IOL) materials resulted in a reduction of 0.08 diopters in the mean defocus generated by LCA. At the retinal plane, the higher Abbe number pseudophakic model produced improvements in polychromatic modulation transfer functions (MTFs) similar to those generated by a 0.05 diopter reduction in spherical defocus. When monochromatic aberrations were added to make the model more representative of actual pseudophakic eyes, the differences in image quality became sub-threshold for human vision or disappeared completely. Conclusion: The anticipated gains in polychromatic image quality from employing higher Abbe number IOL materials with reduced LCA do not materialize in plausible aberrated models of pseudophakic eyes.

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“…In an experimental study, the Clareon CNA0T0 had the lowest levels of axial displacement and corresponding simulated dioptric power shift over all tested compression diameters compared with other one-piece acrylic IOLs, i.e., the MX60 (Bausch & Lomb, Rochester, NY, USA), ZCB00 (Abbott Medical Optics, Santa Ana, CA, USA), and XY1 (HOYA, Tokyo, Japan) IOLs [5]. The current results showed that the ACD was stable at 1 week postoperatively, and the subjective refraction stabilized on day 1 postoperatively.…”

Section: Plos Onementioning

confidence: 93%

“…Several experimental and clinical studies have reported that the new lens had the lowest levels of surface and bulk inhomogeneities and optical characteristics including surface light scattering, glistenings, and chromatic aberration compared to the commercially available IOLs, those resulted in good clinical outcomes [1][2][3][4][5][6][7][8][9][10]. Several previous reports have evaluated the clinical results of the Clareon IOL with the AutonoMe 1 automated delivery system [2,11]; however, no reports have described the early postoperative refractive stability or the postoperative wound-repair process.…”

Section: Introductionmentioning

confidence: 99%

Refractive stability of a new single-piece hydrophobic acrylic intraocular lens and corneal wound repair after implantation using a new automated intraocular lens delivery system

et al. 2020

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To investigate refractive stability and characterize corneal incision repair up to 3 months after implantation of a new hydrophobic acrylic intraocular lens (IOL) with hydroxyethylmethacrylate using a new automated IOL delivery system. Methods This prospective case series included 50 eyes of 50 patients undergoing phacoemulsification and implantation of the Clareon ® CNA0T0 IOL using the AutonoMe ® automated delivery system in the Department of Ophthalmology, Keio University School of Medicine. The clinical data were collected from 46 eyes of 46 patients preoperatively and 1 day, 1 week, and 1 and 3 months postoperatively. Endothelial-side incision gaping, posterior incision retraction, and Descemet's membrane detachment were recorded as present or absent using anteriorsegment optical coherence tomography postoperatively. Results The uncorrected distance and corrected distance visual acuities improved and stabilized 1 week postoperatively. The anterior chamber depth was stable from 1 week postoperatively. The subjective refraction was stable from 1 day postoperatively. Descemet's membrane detachments and endothelial-side wound gaping were seen in 19 (41.3%) eyes and 34 (73.9%) eyes 1 day postoperatively and decreased gradually. Posterior incision retraction was seen in eight eyes (17.4%) on day 1 and increased to 19 eyes (41.3%) 3 months postoperatively.

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Evaluation of intraocular lens mechanical stability

Cited by 33 publications

References 13 publications

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

Visual and refractive outcomes and glistenings occurrence after implantation of 2 hydrophobic acrylic aspheric monofocal IOLs

<p>The Impact of IOL Abbe Number on Polychromatic Image Quality of Pseudophakic Eyes</p>

Refractive stability of a new single-piece hydrophobic acrylic intraocular lens and corneal wound repair after implantation using a new automated intraocular lens delivery system

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