Evaluation of Infiltration of Immunological Cells (Tissue Eosinophil and Mast Cell) in Odontogenic Cysts by Using Special Stains

Debta, Priyanka; Debta, Fakir Mohan

doi:10.4172/2155-9899.1000103

Cited by 7 publications

(7 citation statements)

References 11 publications

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“…Patidar et al, 17 using toluidine blue, found that MCs were observed more commonly in RC, followed by DC and OKC, respectively. Debta et al 19 showed that MCs were associated with RC, OKC and DC, in descending order. They used thionin and toluidine blue to stain MCs.…”

Section: Discussionmentioning

confidence: 99%

Immunohistochemical Assessment of Mast Cells and Small Blood Vessels in Dentigerous Cyst, Odontogenic Keratocyst, and Periapical Cyst

Kouhsoltani¹,

Khiavi²,

Jamali³

et al. 2015

Adv Pharm Bull

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Section: Discussionmentioning

confidence: 99%

Immunohistochemical Assessment of Mast Cells and Small Blood Vessels in Dentigerous Cyst, Odontogenic Keratocyst, and Periapical Cyst

Kouhsoltani¹,

Khiavi²,

Jamali³

et al. 2015

Adv Pharm Bull

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“…On mast cell degranulation various mediators are released therby, playing an important role in the pathogenesis of odontogenic cysts. 12 The hydrostatic pressure of the luminal fluid is essential in cyst enlargement. The increase in the osmotic pressure of the fluid by activated mast cell can be due to following ways-1.…”

Section: Discussionmentioning

confidence: 99%

“…By the histamine action on contraction of smooth muscles and vascular permeability enhances exudation of serum protein following entry into luminal fluid. 12…”

Section: Discussionmentioning

confidence: 99%

Role of mast cells in aetiopathogenesis of radicular cyst

Doddamani¹,

Akshatha²,

Charlotte³

et al. 2020

JOOO

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The aim of this study was to analyse distribution of mast cells in different zones in the capsule of radicular cyst and to determine its role in mechanism of cystic expansion. Materials and Methods: 20 formalin fixed paraffin embedded tissue block from the diagnosed cases of radicular cyst were included and was cut into 5µm thickness. The staining of the tissue sections was done using freshly prepared Toluidine blue solution and mounted using DPX. The mast cell counting was carried out under 20 X magnifications in randomly selected 10 areas and the sections was divided into three zones; Subepithelial, Intermediate and Deep. Result: Mast cells were found to be higher in the Intermediate zone (7.65%) followed by the Subepithelial (13.35%) and Deep zone(6.05%). Kruskal-Wallis test was applied which showed, no significant difference was found between the zones with respect to the mast cells (P>0.05). Conclusion:The present study showed increased activity of mast cell in the intermediate zone indicating breakdown of capsular extracellular matrix in the subepithelial layer as well as enhancing increased osteoclastic activity in the deeper areas thereby leading to the cystic enlargement.

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“…They function in both innate immunity as well as adaptive immunity [36]. Macrophages are believed to help cancer cells proliferate as well.…”

Section: Macrophagesmentioning

confidence: 99%

Immuno Defense Mechanism against Tumors

P¹,

Siddiqui²,

A³

2011

J Cancer Sci Ther

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The hypothesis of immune responses is predicted on theory of immune system that is capable of eliminating foreign antigens including tumor specific antigens in the process, immunosurveillance. To defense against tumors immune system activates cell mediated and humoral immune responses, cell mediated immune system protects the body from itself by controlling cancerous cells, this includes activation of Cytotoxic T Lymphocytes, Natural Killer cells, Macrophages, Dendritic Cells, Lymphokines, etc., where as humoral immune system recognizes foreign particles. These cells play important role in defending as well as in diagnostic processes. Here I discussed about the cell mediated and humoral mediated immuno mechanisms involved in the defense mechanism against tumors.

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Evaluation of Infiltration of Immunological Cells (Tissue Eosinophil and Mast Cell) in Odontogenic Cysts by Using Special Stains

Cited by 7 publications

References 11 publications

Immunohistochemical Assessment of Mast Cells and Small Blood Vessels in Dentigerous Cyst, Odontogenic Keratocyst, and Periapical Cyst

Immunohistochemical Assessment of Mast Cells and Small Blood Vessels in Dentigerous Cyst, Odontogenic Keratocyst, and Periapical Cyst

Role of mast cells in aetiopathogenesis of radicular cyst

Immuno Defense Mechanism against Tumors

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