Evaluation of erectile dysfunction by dynamic infusion cavernosometry and cavernosography (DICC) Multi-institutional study

Kaufman, Joel M.; Borges, Fernando de Almeida; Fitch, William P.; Geller, Reuven A.; Gruber, Michael B.; Hubbard, John G.; McKay, Donald L.; Tuttle, John P.; Witten, Frederick R.

doi:10.1016/0090-4295(93)90505-5

Cited by 38 publications

(15 citation statements)

References 18 publications

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“…Accordingly intracavernosal pressure was allowed to decrease until Doppler signals reappeared. The value where the Doppler signals of cavemosal arteries returned was regarded as cav ernous artery occlusion pressure [8,9]. The difference of this value from the mean systemic arterial blood pressure value was calculated.…”

Section: Methodsmentioning

confidence: 99%

“…However, this requires technical skill and it is an invasive, expensive and uncomfortable method for the patient at best. Color Doppler sonographic evaluation of cavernosal arteries after pharmacologic induction has been widely used to assess arterial components and several studies have been performed to standardize the parameters ob tained [6,7], Measurement of cavernous artery systolic occlusion pressure yields the actual pressure in cavernous artery thus indicating the severity of arterial disease [8,9]. We have performed a prospective study to compare the parameters, peak systolic velocity (PSV) and compliance (diameter changes) of cavemosal arteries after pharmaco logic stimulation with cavernous artery occlusion pressure obtained in dynamic pharmacocavernosometry, in order to determine the validity of the parameters of color Doppler sonography.…”

Section: Introductionmentioning

confidence: 99%

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Judgment of Color Doppler Ultrasound with Respect to Cavernous Artery Occlusion Pressure in Dynamic Infusion Cavernosometry When Evaluating Arteriogenic Impotence

Karadeniz¹,

Topsakal²,

Erton³

et al. 1996

Urol Int

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This prospective study was designed to compare the parameters obtained by color Doppler ultrasound to cavernous artery occlusion pressure measured by dynamic pharmacoinfusion cavernosometry in evaluating arterial components of erectile dysfunction. Four indexes were determined as parameters of sonography to indicate arterial competence. Indexes 1 and 2 reflected peak systolic velocities with respect to the cut-off values 25 and 30 cm/s after pharmacological stimulation with 60 mg papaverine hydrochloride respectively. Index 3 was the percentage of diameter changes in cavemosal arteries which was expected to be > 75%. The sum of the percents of increases in diameters of both cavemosal arteries which should be > 200, formed index 4. The sensitivity, specificity, positive predictive value and accuracy rates were 76, 100, 100 and 90% for index 2. These values were 50, 100, 100 and 71% for index 1. Very low statistical values were obtained for indexes 3 and 4. Although the gold standard in the diagnosis of arterial impotence is pharmacoangiography, color Doppler sonography using the parameter peak systolic flow rate > 30 cm/s may be a reliable, easily obtained, noninvasive technique for evaluating arterial components of erectile dysfunction.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Judgment of Color Doppler Ultrasound with Respect to Cavernous Artery Occlusion Pressure in Dynamic Infusion Cavernosometry When Evaluating Arteriogenic Impotence

Karadeniz¹,

Topsakal²,

Erton³

et al. 1996

Urol Int

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show abstract

“…In patients with suspected veno-occlusive dysfunction (i. e. high end-diastolic velocities), dynamic cavernosometry and cavernosography (DICC) is considered the goldstandard for diagnostics [14]. Dynamic cavernosometry requires the injection of an erection promoting drug to obtain a rigid erection.…”

Section: Venous Imaging and Endovascular Therapy Of Venogenic Edmentioning

confidence: 99%

“…Arteriogenic problems involve any reason for not adequately fi lling the penis with blood, and any failure of the veno-occlusive system is referred to as a venogenic problem. In these patients, dysfunction of the corporal smooth muscle cells leads to incomplete resistance of the blood outfl ow from the corpora [14]. This results in venous leakage, which is frequently associated with an incomplete erection.…”

Section: Introductionmentioning

confidence: 99%

Erectile dysfunction – overview from a cardiovascular perspective

Baumann¹,

Hehli

Makaloski

et al. 2017

Vasa

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Summary:Erectile dysfunction (ED) is an evolving health problem with growing incidence in the ageing male population with potentially predictive value for cardiovascular and other chronic diseases. ED shares the common cardiovascular risk factors. The aetiology of ED is numerous including neurogenic, psychogenic, arteriogenic, and venogenic reasons. The origin of arteriogenic ED is frequently atherosclerosis. Patients not adequately responding to conservative measures including oral medication are often referred to further vascular diagnostics and therapy. At present, the refi nements in endovascular therapy allow for minimal-invasive revascularization of erection-related arteries. The role of endovascular therapy in the complex framework of the multifactorial causes of ED requires further scientifi c scrutiny.

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“…Dynamic infusion cavernosometry and cavernosography studies have also shown that a fluid flow rate between 5 and 40 ml min À1 is required to maintain a normal penis in erect state. 20,21 In the course of this study, parameters such as the thermal conductivity of the skin (A), thermal conductivity of the tunica albuginea (B), perfusion of the sinusoidal space (C) and the blood pressure (D) were taken as analysis factors, which will affect the response of the model. However, it is important to examine the corresponding level of importance of each of the parameters.…”

Section: Sensitivity Analysismentioning

confidence: 99%

The engineering analysis of bioheat equation and penile hemodynamic relationships in the diagnosis of erectile dysfunction: part II—model optimization using the ANOVA and Taguchi method

Huang

et al. 2007

Int J Impot Res

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The authors aimed to study the skin surface bioheat perfusion model described in part I numerically. The influence of each constituent in the determination of surface temperature profile was statistically examined. The theoretically derived data will then be benchmarked with clinically measured data to develop the artificial intelligence system for the diagnosis of erectile dysfunction (ED). The new approach is based on the hypothesis that there exists a constitutive relationship between surface temperature profiles and the etiology of ED. By considering the penis model as a group of reservoirs with irregular cavities, we built a numerical model, simplified to save computational costs while still realistically able to represent the actual for partial differential calculation. Incompressible blood flow was assumed coupled with the classical bioheat transfer equation which was solved using the finite element method. Isotropic homogeneous heat diffusivity was assigned to each tissue layer. The results of simulations were tested for sensitivity analysis and further optimized to obtain the 'best' signal from the simulations using the Taguchi method. Four important parameters were identified and analysis of variance was performed using the 2 n design (n ¼ number of parameters, in this case, 4). The implications of these parameters were hypothesized based on physiological observations. Our results show that for an optimum signal-to-noise (S/N) ratio, the noise factors (thermal conductivity of skin, A and tunica albuginea, B) must be set high and low, respectively. Hence, at this setting, the signal will be captured based on the perfusion rate of the boundary layer of the sinusoidal space and the blood pressure (perfusion of sinusoidal space, C and blood pressure, D) will be optimal as their S/N ratios (C (low) and D (low)) are larger than the former.

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Evaluation of erectile dysfunction by dynamic infusion cavernosometry and cavernosography (DICC) Multi-institutional study

Cited by 38 publications

References 18 publications

Judgment of Color Doppler Ultrasound with Respect to Cavernous Artery Occlusion Pressure in Dynamic Infusion Cavernosometry When Evaluating Arteriogenic Impotence

Judgment of Color Doppler Ultrasound with Respect to Cavernous Artery Occlusion Pressure in Dynamic Infusion Cavernosometry When Evaluating Arteriogenic Impotence

Erectile dysfunction – overview from a cardiovascular perspective

The engineering analysis of bioheat equation and penile hemodynamic relationships in the diagnosis of erectile dysfunction: part II—model optimization using the ANOVA and Taguchi method

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