Ameloblastoma is a type of Odontogenic tumor, commonly encountered in orofacial region. It is very aggressive in nature
with potential features of recurrence. Ki -67 is already a proven proliferative marker, which is used in our study to assess
the proliferative potentiality of Ameloblastoma. Incisional biopsy was done from 10 cases of Ameloblastoma and 5 normal cases as control, at the
department of Oral pathology and Microbiology, BIDSH, Patna. Each specimen was processed and two sections were prepared and stained with
hematoxylin and eosin and Ki-67 immunohistochemical marker. Positive stained cells with with Ki-67 in ameloblastoma along with normal
epithelium were counted from four randomly selected areas and were quantied using a microscope at 400x magnication. Positive correlation
seen with Ki-67 positive cells and percentages, which indicates the value of one variable increases, the other also increases. The overall conclusion
is that Ki-67 expression can be used as a prognostic marker in Ameloblastoma.