Evaluation of endometrial scratching on intrauterine insemination outcome and endometrial receptivity

Gupta, Vasudha; Radhakrishnan, Gita; Arora, Vinod; Singh, Alpana

doi:10.1016/j.mefs.2018.05.002

Cited by 9 publications

(10 citation statements)

References 13 publications

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“…of follicles of size more than 14mm was 3.4+ 1.5 in cases and 3.2+1.3 in controls and there was no statistically significant difference. While Gupta et al 13 in their study showed a statistically significant difference between both the groups. No.…”

Section: Discussionmentioning

confidence: 71%

“…Mean endometrial thickness was 8.33+ 0.97 in cases and 10.5+ 1.37 in controls in their study. On the other hand, Gupta et al [13] found higher endometrial thickness in cases (9.18+ 3.35) as compared to controls (8.53 +1.88). Pregnancy rate in our study was 14%.…”

Section: Discussionmentioning

confidence: 91%

“…Number of clinical pregnancies in the case group and control group was 10 and 4 respectively (p value =0.022). In a study conducted by Hamdi et al [15] , pregnancy rate was 21% and it was 19% in study by Gupta et al [13] . On the other hand Zarei et al [14] indicated that local endometrium injury before IUI is not accompanied by increased pregnancy rate.…”

Section: Discussionmentioning

confidence: 92%

“…For instance, in a study by Hamdi et al [15] , the better time considered was day1-5 of the same menstrual cycle. Gupta et al [13] showed that promising results are obtained when the endometrial scratch is carried out on day 20-22 of the cycle preceding IUI. While Zarei et al [14] performed endometrial scratch one month prior to IUI on day 6-8.…”

Section: Discussionmentioning

confidence: 99%

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Uterine cavity coring before intra-uterine insemination in patients with unexplained infertility

Dogra¹,

Kumar²,

Kumar³

2020

Int. J. Clin. Obstet. Gynaecol.

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Introduction: Infertility, a major health problem nowadays, affects around 8-12% of couples worldwide. Unexplained infertility affects up to 15-30% of infertile couples. Management options for unexplained infertility are expectant management, timed intercourse, IUI with or without controlled ovarian stimulation, ART i.e IVF/intracytoplasmic sperm injection (ICSI). Endometrial mechanical injury in order to augment the probability of implantation of embryo and pregnancy rate has been particularly noted in recent years. Objectives: Evaluation of endometrial scratching on pregnancy rates after IUI. Material and methods: This interventional study was carried out in SMGS Hospital, GMC Jammu over a period of 18 months from July 2018 to December 2019. A total of 100 infertile women with unexplained infertility were included in the study and were randomly divided into two groups, 50 in each. The IUI procedure was carried out in the first group after the endometrial scratch on day 2-3 of menstrual cycle, while the control group underwent only IUI without any intervention. The pregnancy rates were compared in both the groups. Results: Among 100 patients who entered this study, 14 (14%) women got pregnant. There were 10 (10%) clinical pregnancies in the study group and 4 (4%) in the control group. Therefore 71% of the pregnant cases in this study were from the case group, showing the two-thirds of the success in treating infertile couple in this study belonged to scratching method. There was a significant difference in between both the groups. Conclusions: The uterine cavity coring (endometrial scratching) performed on day2-3 of the menstrual cycle, preceding IUI procedure, leads to a significant increase in pregnancy rate. On the other hand, this method can be employed with lower costs in comparison to other fertilisation methods.

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Section: Discussionmentioning

confidence: 71%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Uterine cavity coring before intra-uterine insemination in patients with unexplained infertility

Dogra¹,

Kumar²,

Kumar³

2020

Int. J. Clin. Obstet. Gynaecol.

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“…Evaluation of this procedure in failed IUI cycles is even less studied. 5 Abdelhamid AMS et al 6 first reported the beneficial effects of endometrial injury in previous failed IUI cycles in their study published in the year as recent as 2013 almost a decade after the first report in IVF cycle.…”

Section: Discussionmentioning

confidence: 99%

To Analyse the Effect of Endometrial Scratching on Pregnancy Rates in Previously Failed Iui Cycles

Joshi

Gupta

2021

IJMBS

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Background: To analyse the effect of endometrial scratching on pregnancy rates in previously failed IUI cycles Methods: Randomized control study conducted on Couples attending the Infertility Clinic, Obstetrics & Gynaecology Department, SMS Medical College, Jaipur and requiring repeat IUI were recruited for the study from Feb 2019 to November 2020. Results: women in which IUI failed two times positive results after scratching was present in 16.15% cases followed by 6.92% positive results in women who had three times IUI failed and women who had only one-time IUI failed positive results was present in 4.62% cases. In controls we found positive results with 5.38% in women having one-time IUI failed followed by 3.85% in women where two time IUI failed and only in 2.31% women positive results found having three time IUI failed. Conclusion: In conclusion this study demonstrates 2.5-3 fold increase in pregnancy rates after scratch, endometrial scratching can be a preferred option in patients with previous failed IUI cycles before opting for expensive IVF treatment. Keywords: IUI, IVF, Inferetility

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Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination

Bui

Lensen

Gibreel

et al. 2021

Cochrane Database of Systematic Reviews

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Evaluation of endometrial scratching on intrauterine insemination outcome and endometrial receptivity

Cited by 9 publications

References 13 publications

Uterine cavity coring before intra-uterine insemination in patients with unexplained infertility

Uterine cavity coring before intra-uterine insemination in patients with unexplained infertility

To Analyse the Effect of Endometrial Scratching on Pregnancy Rates in Previously Failed Iui Cycles

Endometrial injury for pregnancy following sexual intercourse or intrauterine insemination

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