Background: To analyse the effect of endometrial scratching on pregnancy rates in previously failed IUI cycles
Methods: Randomized control study conducted on Couples attending the Infertility Clinic, Obstetrics & Gynaecology Department, SMS Medical College, Jaipur and requiring repeat IUI were recruited for the study from Feb 2019 to November 2020.
Results: women in which IUI failed two times positive results after scratching was present in 16.15% cases followed by 6.92% positive results in women who had three times IUI failed and women who had only one-time IUI failed positive results was present in 4.62% cases. In controls we found positive results with 5.38% in women having one-time IUI failed followed by 3.85% in women where two time IUI failed and only in 2.31% women positive results found having three time IUI failed.
Conclusion: In conclusion this study demonstrates 2.5-3 fold increase in pregnancy rates after scratch, endometrial scratching can be a preferred option in patients with previous failed IUI cycles before opting for expensive IVF treatment.
Keywords: IUI, IVF, Inferetility
Foetal nasal bone length vary in different ethnic groups, its rate of growth in a particular group can be accurately measured. This increase in foetal nasal bone length can be used as a reference range for that particular group.
OBJECTIVEThis study is an attempt to evaluate a reference range of foetal nasal bone length from 15 wks. to full term in North Indian population and to find the difference with other ethnic groups during the same period of gestation.
MATERIAL AND METHODPregnant women undergoing ultrasonography from 15 wks. till term with a single live foetus having no complication either in the foetus or mother were selected for the study. All parameters i.e. BPD, AC, FL, kidney length, nasal bone length measurements and their rate of growth were calculated and findings were compared with other authors.
RESULTSThe rate of growth of foetal nasal bone length during different weeks of gestation showed correlation described by the following equation NBL=0.349XGA+0.440 with goodness of fit estimate R 2 =0.969 with a constant p value <0.0001. There was a significant difference in length of foetal nasal bone length in different ethnic groups. Our results in North Indian population were similar to that of South Indian, Caucasians, Brazilian population, but very different from that of Chinese and Japanese population.
CONCLUSIONThe data can be used in estimation of GA by NBL as the estimation of NBL is accurate and the increase per week of gestation shows a linear increase in Indian population.
KEYWORDSFoetal Nasal Bone, Normal Range, North Indian Women.
HOW TO CITE THIS ARTICLE:Gupta DP, Gupta RP, Saxena DK, et al. Study of foetal nasal bone length during 15-38 weeks of gestation in women of Northern India (U.P.) and its comparison with Western and other Asian women.
Background:
Methods: The present study is a single arm interventional study done at a tertiary care hospital in a metropolitan city. The study participants were the females who had infertility due to PCOS and resistant to clomiphene citrate, and participants were given HMG in a sequential manner with Clomiphene citrate and ovulation was observed using the TVS.
Results: 79% of the study participants ovulated at the end of the study as a final outcome and only 25 participants who constitute 21% of the total had not ovulated. No cases of ovarian hyperstimulation and multiple gestation was reported.
Conclusion: The study thus concludes that CC with low dose HMG is an efficient and safe method for induction of ovulation in females with CC resistant PCOS related infertility without the dangers of OHSS and other adverse events, also the presence of normal BMI can help in a better rate of ovulation
Keywords: HMG, TVS, Infertility
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