“…Both deiodinases have an important role for maintaining local T3 levels in the brain and pituitary in vivo. The T-Screen assay successfully predicted the effects of certain thyroid hormone disrupting chemicals, such as plasticizers, alkylphenols, pesticides, polychlorinated biphenyls, brominated flame-retardants and personal care products (Ghisari and BonefeldJorgensen, 2005;Hamers et al, 2006;Schriks et al, 2006;Hansen et al, 2009;Taxvig et al, 2011;Hinther et al, 2011).…”