Evaluation of embouchure dysfunction: Experience of 139 patients at a single center

Termsarasab, Pichet

doi:10.1002/lary.25723

Cited by 15 publications

(23 citation statements)

References 14 publications

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“…There are no effective treatments for focal embouchure dystonia (FED). 6 A subset of affected individuals have progression of their symptoms to involve additional orofacial tasks, 5,6 but the risk factors for generalization remain unknown.…”

Section: Introductionmentioning

confidence: 99%

“…Dystonia in brass musicians most commonly involves the embouchure, the positioning of orofacial muscles used to play a wind instrument. There are no effective treatments for focal embouchure dystonia (FED) . A subset of affected individuals have progression of their symptoms to involve additional orofacial tasks, but the risk factors for generalization remain unknown.…”

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confidence: 99%

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Quantitative, clinically relevant acoustic measurements of focal embouchure dystonia

et al. 2018

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Acoustic variables distinguish musicians with embouchure dystonia from controls and reflect different types of symptomatic impairments. Our composite acoustic severity score predicts severity of clinical global impression for musicians with different patterns of symptomatic impairment and may provide a foundation for developing a clinical rating scale. © 2018 International Parkinson and Movement Disorder Society.

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Section: Introductionmentioning

confidence: 99%

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confidence: 99%

Quantitative, clinically relevant acoustic measurements of focal embouchure dystonia

et al. 2018

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“…In focal/segmental dystonia, medical treatment may have a primary role when BoNT is not technically feasible, or where BoNT is prone to side effects or functional impairment such as tongue or embouchure dystonia [188]. In general, location of dystonia does not impact the choice of medication.…”

Section: Reviewmentioning

confidence: 99%

Medical treatment of dystonia

2016

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Therapeutic strategies in dystonia have evolved considerably in the past few decades. Three major treatment modalities include oral medications, botulinum toxin injections and surgical therapies, particularly deep brain stimulation. Although there has been a tremendous interest in the later two modalities, there are relatively few recent reviews of oral treatment. We review the medical treatment of dystonia, focusing on three major neurotransmitter systems: cholinergic, GABAergic and dopaminergic. We also provide a practical guide to medication selection, therapeutic strategy and unmet needs.

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“…To elucidate these issues, we examined patients with embouchure dystonia (ED) as an example of FTSD, using fMRI during both embouchure and somatotopy tasks. ED is a type of FTSD affecting the lip, jaw, tongue, facial, laryngeal, or masticatory muscles, such as involuntary tremor or lip‐pulling while controlling air flow into the mouthpiece of a wind instrument such as trombone, trumpet, or horn (Frucht, , ; Iltis et al, ; Termsarasab & Frucht, ). Previous imaging studies reported aberrant brain activity in sensorimotor areas while patients with ED blew into an MRI‐compatible mouthpiece (Haslinger et al, ).…”

Section: Introductionmentioning

confidence: 99%

Distinct roles of brain activity and somatotopic representation in pathophysiology of focal dystonia

Uehara

Furuya

Numazawa

et al. 2018

Human Brain Mapping

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Two main neural mechanisms including loss of cortical inhibition and maladaptive plasticity have been thought to be involved in the pathophysiology of focal task‐specific dystonia. Such loss of inhibition and maladaptive plasticity likely correspond to cortical overactivity and disorganized somatotopy, respectively. However, the most plausible mechanism of focal task‐specific dystonia remains unclear. To address this question, we assessed brain activity and somatotopic representations of motor‐related brain areas using functional MRI and behavioral measurement in healthy instrumentalists and patients with embouchure dystonia as an example of focal task‐specific dystonia. Dystonic symptoms were measured as variability of fundamental frequency during long tone playing. We found no significant differences in brain activity between the embouchure dystonia and healthy wind instrumentalists in the motor‐related areas. Assessment of somatotopy, however, revealed significant differences in the somatotopic representations of the mouth area for the right somatosensory cortex between the two groups. Multiple‐regression analysis revealed brain activity in the primary motor and somatosensory cortices, cerebellum, and putamen was significantly associated with variability of fundamental frequency signals representing dystonic symptoms. Conversely, somatotopic representations in motor‐related brain areas were not associated with variability of fundamental frequency signals in embouchure dystonia. The present findings suggest that abnormal motor‐related network activity and aberrant somatotopy correlate with different aspects of mechanisms underlying focal task‐specific dystonia.

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Evaluation of embouchure dysfunction: Experience of 139 patients at a single center

Abstract: 4. Laryngoscope, 126:1327-1333, 2016.

Cited by 15 publications

References 14 publications

Quantitative, clinically relevant acoustic measurements of focal embouchure dystonia

Quantitative, clinically relevant acoustic measurements of focal embouchure dystonia

Medical treatment of dystonia

Distinct roles of brain activity and somatotopic representation in pathophysiology of focal dystonia

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