Evaluation of diagnostic tests: dengue

Serological and Epidemiological Picture of Dengue during the Year 2014: An Exclusive Study of Kutch District, Gujarat, India

“…However almost half (81, 48.8%) patients from total 166 patients who came within 2 days of fever were tested positive for Dengue. This could be due to high sensitivity and specificity of Dengue NS 1 antigen ELISA test which was the sole test selected for patients presents early in acute stage of Dengue (Kulkarni et al, 2011;Peeling et al, 2010).…”

Thrombocytopenia – An Indicator of Impending Complications in Dengue Virus Infection

“…However, this is not within the reach of peripheral and even most tertiary care laboratories (Peeling et al, 2010;Kulkarni et al, 2011).…”

“…Laboratory confirmation of dengue infection relies on isolation of the virus in cell culture, the identification of viral nucleic acid or antigens, or the detection of virus specific antibodies (Peeling et al, 2010).…”

Discovery and Characterization of Potential Prognostic Biomarkers for Dengue Hemorrhagic Fever

“…Although methods for dengue diagnosis are well established, there are no prognostic tests to help the clinician evaluate the risk of progressing to severe dengue. 2 This is especially important because often the onset of severe disease occurs as the patient's fever is resolving. 3 Previously identified markers of dengue severity include cytokines (i.e., tumor necrosis factor alpha [TNFα] and Interleukin 6 [IL-6]), vascular permeability proteins, clotting cascade regulators, and gene expression profiles.…”