Serological and Epidemiological Picture of Dengue during the Year 2014: An Exclusive Study of Kutch District, Gujarat, India

Gusani, Jigar Kiritkumar; Assudani, Hitesh; Kothari, Krupali; Ghosh, Anupam

doi:10.20546/ijcmas.2017.605.234

Cited by 2 publications

(1 citation statement)

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“…Literature search suggests that there is scarcity of specific & exclusive data on prevalence of Dengue in Kutch region. 8 The present study was carried out to find out data on Dengue specific serological markers like NS1 antigen, IgM antibody and epidemiological characteristics of dengue infections during the year 2019 in Kutch region of Gujarat State, India.…”

Section: Introductionmentioning

confidence: 99%

Epidemiological and demographic characteristics of dengue at a tertiary care center in Kutch region during the year 2019

Chavda

Patel²,

Kinariwala³

et al. 2023

IJMMTD

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Dengue is the most rapidly spreading mosquito borne viral disease of mankind, with a 30 fold increase in global incidence over the last five decades. It is a major public health concern throughout the tropical and subtropical regions of the world. The present study was conducted with objective to study epidemiological and demographic characteristics of dengue infection during the year 2019 in Kutch region, Gujarat, India.The study was carried out from January 2019 to December 2019 at Department of Microbiology, Gujarat Adani Institute of Medical Sciences, G.K. General Hospital, Bhuj. The patients having suspected dengue fever was based on standard criteria like presentation of febrile illness of 2-7 days duration were included in this study.A total of 1509 blood samples were collected during study period and serologically tested for dengue NS1 antigen and IgM antibody by capture ELISA testing method. Total 1509 blood samples were tested by ELISA for NS1 antigen and/or IgM antibody as per the protocols and personal, demographic and clinical details of each patient was recorded. Out of 1509 cases 761 tested positive for dengue. Amongst all positive cases 533(47%) were tested positive for NS1 antigen which helped in early diagnosis of dengue. Rise of dengue cases started after the month of October and falls down by the end of December. Analysis of this data revealed that age group 00-10 years had maximum dengue cases. Male cases 418(55%) were more than females 343(45%). Dengue cases were high in urban area.The present study reported that dengue mainly affected children, males and urban population. Perennial occurrence with seasonal increase during monsoon and post monsoon moths was reported. Effective implementation of vector control measures through efforts toward vector breeding source reduction and with the use of personal prophylactic measures against mosquito bites will help in reducing the dengue prevalence in the community.

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Section: Introductionmentioning

confidence: 99%

Epidemiological and demographic characteristics of dengue at a tertiary care center in Kutch region during the year 2019

Chavda

Patel²,

Kinariwala³

et al. 2023

IJMMTD

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Dengue infection in India: A systematic review and meta-analysis

et al. 2018

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IntroductionDengue is the most extensively spread mosquito-borne disease; endemic in more than 100 countries. Information about dengue disease burden, its prevalence, incidence and geographic distribution is critical in planning appropriate control measures against dengue fever. We conducted a systematic review and meta-analysis of dengue fever in IndiaMethodsWe searched for studies published until 2017 reporting the incidence, the prevalence or case fatality of dengue in India. Our primary outcomes were (a) prevalence of laboratory confirmed dengue infection among clinically suspected patients, (b) seroprevalence in the general population and (c) case fatality ratio among laboratory confirmed dengue patients. We used binomial–normal mixed effects regression model to estimate the pooled proportion of dengue infections. Forest plots were used to display pooled estimates. The metafor package of R software was used to conduct meta-analysis.ResultsOf the 2285 identified articles on dengue, we included 233 in the analysis wherein 180 reported prevalence of laboratory confirmed dengue infection, seven reported seroprevalence as evidenced by IgG or neutralizing antibodies against dengue and 77 reported case fatality. The overall estimate of the prevalence of laboratory confirmed dengue infection among clinically suspected patients was 38.3% (95% CI: 34.8%–41.8%). The pooled estimate of dengue seroprevalence in the general population and CFR among laboratory confirmed patients was 56.9% (95% CI: 37.5–74.4) and 2.6% (95% CI: 2–3.4) respectively. There was significant heterogeneity in reported outcomes (p-values<0.001).ConclusionsIdentified gaps in the understanding of dengue epidemiology in India emphasize the need to initiate community-based cohort studies representing different geographic regions to generate reliable estimates of age-specific incidence of dengue and studies to generate dengue seroprevalence data in the country.

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Serological and Epidemiological Picture of Dengue during the Year 2014: An Exclusive Study of Kutch District, Gujarat, India

Cited by 2 publications

References 10 publications

Epidemiological and demographic characteristics of dengue at a tertiary care center in Kutch region during the year 2019

Epidemiological and demographic characteristics of dengue at a tertiary care center in Kutch region during the year 2019

Dengue infection in India: A systematic review and meta-analysis

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