Evaluation of cytotoxic properties of organometallic ferrocifens on melanocytes, primary and metastatic melanoma cell lines

A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines

“…In fact, previous studies on OH-TAM induced apoptosis of MCF-7 cells have shown that this effect is connected to NOS (nitrogen oxygen species) [33], and the probe used in our experiments (H 2 DCFDA) is almost totally specific for hydroperoxide (H 2 O 2 ) [32]. On the other hand, ROS production was not observed on melanoma cells, while Fc-OH-TAM also showed an anti-proliferative effect on these cells [38]. This result was rather puzzling at first glance.…”

Ferrocene–indole hybrids for cancer and malaria therapy

“…For C 24 H 20 FeN 2 : C,73.48;H,5.14;N,7.14. Found: C,73.10;H,5.04;N,6.83%. MS (ESI þ IR: 3500, 3404, 3200, 3087, 2921IR: 3500, 3404, 3200, 3087, , 1764IR: 3500, 3404, 3200, 3087, , 1590IR: 3500, 3404, 3200, 3087, , 1563IR: 3500, 3404, 3200, 3087, , 1451IR: 3500, 3404, 3200, 3087, , 1337IR: 3500, 3404, 3200, 3087, , 1320IR: 3500, 3404, 3200, 3087, , 1104 …”

“…For C 25 H 21 FeN: C,76.92;H,5.37;N,3.58. Found: C,76.59;H,5.31;N,3.78%. MS (ESI þ IR: 3500, 3403, 3383, 1456, 765, 746, 699, 501, 484.…”

New lanthanide complexes of 1,1`-bis[(2-thienylmethylidene)hydrazono-1-ethyl]-ferrocene and 1,1`-bis(2,3-dihydro-2-methylbenzo[d]thiazol-2-yl)ferrocene: Synthesis, characterization and antimicrobial properties

“…In the past few years, the versatile chemistry of ferrocene has attracted the attention of many researchers [1][2][3][4][5][6][7][8][9][10][11][12][13]. It has been used as a precursor for the preparation of coordination and biologically active compounds.…”