Evaluation of clinical and metabolic changes after non surgical periodontal treatment of type 2 diabetes mellitus patients: A clinico biochemical study

Abstract

Aim:To evaluate the clinical and metabolic changes following nonsurgical periodontal therapy of type-2 diabetic patients and nondiabetic patients.Materials and Methods:Fifteen nondiabetics and fifteen type-2 diabetics with moderate to severe periodontitis were selected after meeting inclusion and exclusion criteria. Periodontal pocket probing was performed using a Williams graduated periodontal probe and comparisons of the clinical and biochemical parameters like plaque index, gingival index, probing depth, glycated hemoglobin, and lipid profile (total cholesterol, high density lipoprotein, low density lipoprotein, triglycerides and very low density lipoprotein) were done between and within two groups at baseline and 3 month.Results:A correlation was observed between clinical and biochemical parameters between and within two groups at baseline and 3 month. The P value of diabetic group was<0.001 in all clinical parameters (plaque index PI, Gingival index GI, and Probing Pocket Depth PPD) in diabetic and nondiabetic group, showed statistically highly significant difference in GI, PI, PPD, <.01 in Glycated Hemoglobulin (HbAlc1) in test group and<0.05 in control group showed statistically significant difference. The P value of test group was >0.05 in Lipid profile (total cholesterol, low density lipoprotein, high density lipoprotein, serum triglyceride, very low density lipoprotein) that showed no significant difference and in control group<0.05 in total Cholesterol, high density lipoprotein and <0.01 in Low density lipoprotein, Very Low Density Lipoprotein, and Serum Triglyceride, respectively, showed statistically significant in Total cholesterol, Low density lipoprotein, Very Low Density Lipoprotein, and Serum Triglyceride, not significant in high density lipoprotein. The P value >0.05 showed no statistical significance of correlation between the test and control groups.Conclusion:Both groups of patients showed an improvement in clinical and metabolic parameters assessed at 3 months after nonsurgical periodontal therapy.

Effectiveness of Periodontal Treatment to Improve Metabolic Control in Patients With Chronic Periodontitis and Type 2 Diabetes: A Meta‐Analysis of Randomized Clinical Trials

“…Therefore, 72 articles were assessed for elegibility 1,7,[11][12][13][14][15][16] (inter-reviewer agreement, k = 0.79). Of these, 61 articles 11,[13][14][15][16]26,[28][29][30][31][32][33][34][35][36][37][38][39]41,43,44,[46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][62][63][64][65][66][67][68][69]…”

“…Therefore, 72 articles were assessed for elegibility 1,7,11‐16,26‐89 (inter‐reviewer agreement, κ = 0.79). Of these, 61 articles 11,13‐16,26,28‐39,41,43,44,46‐60,62‐69,71‐73,75‐85,87‐89 were excluded during the first phase of the study selection process for not satisfying ≥1 inclusion criteria (inter‐reviewer agreement, κ = 0.77). Six 27,40,42,45,70,86 of the remaining studies were excluded during the second phase of the selection process for meeting ≥1 exclusion criteria (inter‐reviewer agreement, κ = 1).…”

Effect of scaling and root planing on serum interleukin-10 levels and glycemic control in chronic periodontitis and type 2 diabetes mellitus

“…This is in agreement with studies by Stewart et al .,[ 4 ] Kiran et al .,[ 5 ] Jones et al .,[ 6 ] Singh et al .,[ 23 ] and other studies. [ 24 25 26 27 ]…”

Efeitos clínicos e metabólicos da terapia periodontal não cirúrgica em pacientes diabéticos e não diábeticos - revisão de literatura

“…Nos estudos de Da Cruz et al 17 foram melhorados o índice de placa em todos os tempos para diabéticos e não diabéticos após 3 meses, assim como o índice de sangramento gengival. Resultados semelhantes com respeito a essas variáveis foram encontradospor outros autores para o índice de placa 8,12,13,16,18,19,25 e índice gengival. 8,13,16,18,19 A redução significativa desses parâmetros após a terapia confirma a eficácia do controle de higiene oral e redução da inflamação gengival.…”

“…O nível clínico de inserção também reduziu após o tratamento nãocirúrgico nos estudos realizados por Navarro-Sanchez, Faria-Almeida e Bascones-Martinez. 20 No entanto, Da Cruz et al 17 não encontrou diferenças estatisticamente significativas para ambos os grupos, assim como outros autores 8,13,18,19 quando comparados diabéticos com não diabéticos após o tratamento periodontal.…”