Evaluation of aspiration cytology of ovarian masses with histopathological correlation

Abstract

FNAC of ovarian masses is a minimally invasive procedure that can differentiate neoplastic from non-neoplastic ovarian lesions. It may help avoid unnecessary operations and preserve the reproductive ability in young patients. Furthermore, it also enables a satisfactory sub-categorization of ovarian tumours, which facilitates the choice of appropriate therapy.

Fine-Needle Aspiration Biopsies of Ovarian Masses: A Reliable Technique

“…The surface epithelial group (either benign or malignant) in our study showed an excellent cytological and pathological correlation, as was also seen in the studies by Sood et al [9] and Gupta et al [10]. We had no false positive results in this category, leading to a positive predictive value of 100% in tumors in the surface epithelial category.…”

http://www.omicsonline.org/open-access/accuracy-of-combined-tru-cut-and-fnac-in-preoperative-sampling-of-ovarian-tumors-2161-0681.1000168.php?aid=26242

“…Only Freedman et al [4], and Sood et al [14] discussed the accuracy of FNAC for tumor typing similar to our study. In both studies ability for estimation of tumor type (83.8% for Sood et al, and 55% for Freedman et al) was higher than that in our study (39.4%).…”

“…On the other hand, the diagnostic accuracy for FNAC in our study was within the range reported by most of the studies like that of Bandyopadhyay et al [6], Sood et al [14], Freedman et al [4], Hemalatha et al [17], and Gupta et al [16], that were (97.06%, 98%, 96.2%, 96.3%, 92% respectively). But it was slightly higher than that reported by Khan et al [19] that was (89.9%) and Stewart et al [23] that was (86.5%), and prominently higher than that reported by Mehdi et al [13] that was (80.9%).…”

“…Considering the role of FNAC alone, it was addressed in more studies some of which were specific for ovarian masses including Bandyopadhyay et al [6], Mehdi et al [13], Sood et al [14], Goel et al [15], and Gupta et al [16]. Others like Hemalatha et al [17] studied the role of FNAC in abdomino-pelvic masses in general including ovarian masses as part of their studied population.…”

Accuracy of Fine Needle Aspiration of Pelvic Masses, A Cyto-histological Correlation

“…According the results of their study the positive predictive value was 100% and negative predictive value 90.9% and the overall diagnostic accuracy was 96.2 % [18]. Recently Gupta et al, in a retrospective study of ultrasound-guided (US) FNAC of 584 ovarian lesions evaluated that FNAC sensitivity for a diagnosis of malignancy was 85.7%, specificity 98.0%, positive predictive value 97.7%, negative predictive value 87.7% and accuracy 92.0%.…”