Abstract:Background: Analgesics selectively relieve pain by acting either on central or peripheral pain pathways. Recently, studies have shown accumulating evidence to implicate N-methyl-d-aspartate receptors (NMDARs) mediation in central and peripheral sensitization and visceral pain leading to the possibility that NMDAR antagonists may be useful in the treatment of pain. Aims and Objectives: (1) To evaluate analgesic activity of Pioglitazone (PIO) in mice. (2) To compare the analgesic activity of PIO with the standar… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.