Evaluation of 39 cases of pediatric cutaneous head and neck melanoma

Tcheung, Win J.; Marcello, Jennifer; Puri, Puja K.; Abernethy, Amy P.; Nelson, Kelly C.

doi:10.1016/j.jaad.2010.10.003

Cited by 12 publications

(15 citation statements)

References 15 publications

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“…However, our results demonstrate a trend toward higher incidence of scalp and neck melanoma in boys. Similar findings were found in a study by Tcheung et al 23 in 39 pediatric head and neck melanoma cases. The authors concluded that the scalp and neck were the most common sites for head and neck melanoma, with an increased incidence in males.…”

Section: Discussionsupporting

confidence: 92%

Pediatric melanoma: Characterizing 256 cases from the Colorado Central Cancer Registry

Kalani

Guidry

Farahi

et al. 2019

Pediatric Dermatology

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Background Melanoma is a rare diagnosis in the pediatric population. Differences in incidence, presentation, and survival distinguish pediatric melanoma from adult melanoma. In order to improve our understanding of pediatric melanoma, our case series investigates differences in incidence, age of onset, and anatomic site between male and female pediatric melanoma patients in Colorado between 1988 and 2015. Methods All data were gathered from the Colorado Central Cancer Registry. A request for de‐identified data on pediatric melanoma patients between 1988 and 2015 was made by the University of Colorado Department of Dermatology. Chi‐square tests were used to compare the differences reported in melanoma between sex, age‐groups, and site of lesion. Results A total of 256 cases of melanoma were reported in Colorado in patients < 20 years of age between 1988 and 2015. Overall incidence of pediatric melanoma in Colorado increased from 1988 to 1999 but declined from 2001 to 2011. There was a significant predominance of female cases in the 10‐14 age‐group (P = 0.0477) and 15‐19 age‐group (P = 0.0472). Both groups had increased incidence of melanoma with increasing age. The mean age of onset for both sexes was 16 years old. Boys were more likely to have melanoma of the scalp and neck (P = 0.0523) and less likely to have melanoma of the leg (P = 0.0049). Conclusion Among the pediatric population, girls 10‐14 and 15‐19 years old are at a significantly increased risk of melanoma compared to boys in these age‐groups. Our study found sex‐specific differences in anatomic site consistent with prior literature. Further investigations should aim to identify causes for these sex‐specific differences in order to better guide public health initiatives.

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Section: Discussionsupporting

confidence: 92%

Pediatric melanoma: Characterizing 256 cases from the Colorado Central Cancer Registry

Kalani

Guidry

Farahi

et al. 2019

Pediatric Dermatology

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“…Prompted by concern about the large size, irregular borders and colour variegation of scalp naevi, clinicians and parents may request excision of these naevi. Although melanoma of the scalp does occur in childhood, 12 frequently such excisions demonstrate naevi with mild to moderate atypia. The indiscriminate removal of scalp naevi may lead to heightened anxiety among patients and their parents, along with scarring, pain, and further procedures as new scalp naevi are found.…”

Section: Discussionmentioning

confidence: 99%

“…Boys exhibited significantly more scalp naevi (3·3 naevi per boy) compared with girls (1·3 naevi per girl) ( P = 0·0005). Interestingly, in a study on paediatric head and neck melanoma, most subjects with scalp/neck melanoma were also male 12 . The higher incidence of melanoma of the scalp in boys could be attributed to boys possessing more scalp naevi, as melanoma may develop from existing naevi.…”

Section: Discussionmentioning

confidence: 99%

Clinical and dermoscopic features of 88 scalp naevi in 39 children

Tcheung

Bellet²,

Prose³

et al. 2011

British Journal of Dermatology

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Summary Background Paediatric scalp nevi may represent a source of anxiety for practitioners and parents, as the clinical and dermoscopic features of typical nevi have yet to be defined. Prompted by concern about the large size, irregular borders, and colour variation of scalp nevi, clinicians and parents may request unnecessary excision of these nevi. Objective The purpose of this study is to establish the typical clinical and dermoscopic patterns of scalp nevi in children younger than 18 years old to help optimize clinical care and management. Methods Scalp nevi were imaged with a camera (Canon Rebel, XSi) and dermoscopic attachment (3Gen, Dermlite Foto, 30mm lens) to the camera. The clinical and dermoscopic images were reviewed and analyzed. Both acquired and congenital scalp nevi were included but were not further differentiated from each other. Results We obtained clinical and dermoscopic images of 88 scalp nevi in 39 Caucasian children. Two subjects had received chronic immunosuppressive medication. Nineteen children have had a family history of melanoma. Males (18/39 subjects, 46%) possessed 68% (60 nevi) of scalp nevi imaged. Younger (<10 years old) subjects (24/39 subjects, 62%) possessed 42% (37 nevi) of scalp nevi. The main clinical patterns included eclipse (n=18), cockade (n=3), solid brown (n=42), and solid pink (n=25) nevi. Solid-coloured nevi showed the following dermoscopic patterns: globular (57%), complex (reticular-globular) (27%), reticular (9%), homogenous (6%), and fibrillar (1%). The majority of nevi had a unifying feature—perifollicular hypopigmentation, which caused the appearance of scalloped, irregular borders if occurring on the periphery, or variegation in pigmentation, if occurring within the nevi. Conclusions Older subjects and males tend to harbour a larger proportion of scalp nevi. The main clinical patterns include solid-coloured and eclipse nevi. The most common dermoscopic pattern of scalp nevi is the globular pattern. Perifollicular hypopigmentation is a hallmark feature of signature scalp nevi. Dermoscopy is a non-invasive tool in the evaluation of cutaneous melanocytic lesions in children and may decrease the number of unnecessary excisions.

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“…Whereas melanoma of the scalp does occur in childhood [41], indiscriminate removal of scalp nevi may lead to heightened anxiety among patients and unnecessary procedures. To improve clinical management, Tcheung and colleagues recently sought to establish the typical clinical and dermatoscopic patterns of scalp nevi in children younger than age 18 years [42•].…”

Section: Dysplastic Nevimentioning

confidence: 99%

Literature Update on Melanocytic Nevi and Pigmented Lesions in the Pediatric Population

2012

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Pigmented lesions and melanocytic nevi are commonly evaluated lesions in pediatric dermatology clinics and the rising incidence of melanoma has increased public awareness of malignant potential. Diagnosis and management of pigmented lesions, especially dysplastic nevi, medium and large congenital melanocytic nevi (CMN), and Spitz nevi, can be particularly challenging. We summarize the recent literature for melanocytic nevi and pigmented lesions as relevant to the practice of pediatric dermatology with particular attention to dermatoscopic techniques, histopathologic interpretation, molecular biology, and management recommendations for CMN and Spitz nevi.

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Evaluation of 39 cases of pediatric cutaneous head and neck melanoma

Cited by 12 publications

References 15 publications

Pediatric melanoma: Characterizing 256 cases from the Colorado Central Cancer Registry

Pediatric melanoma: Characterizing 256 cases from the Colorado Central Cancer Registry

Clinical and dermoscopic features of 88 scalp naevi in 39 children

Literature Update on Melanocytic Nevi and Pigmented Lesions in the Pediatric Population

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