Literature Update on Melanocytic Nevi and Pigmented Lesions in the Pediatric Population

Abstract

Pigmented lesions and melanocytic nevi are commonly evaluated lesions in pediatric dermatology clinics and the rising incidence of melanoma has increased public awareness of malignant potential. Diagnosis and management of pigmented lesions, especially dysplastic nevi, medium and large congenital melanocytic nevi (CMN), and Spitz nevi, can be particularly challenging. We summarize the recent literature for melanocytic nevi and pigmented lesions as relevant to the practice of pediatric dermatology with particular attention to dermatoscopic techniques, histopathologic interpretation, molecular biology, and management recommendations for CMN and Spitz nevi.

A Case of Colocalized Vitiligo and Psoriasis

“…Up to half of vitiligo patients are reported to have these lesions, and theories suggest that both phenomena arise from an autoimmune reaction to pigmented cells in the nevus and in normal skin. 14,15 Examination revealed no halo nevi in this patient.…”

Discriminant models of the possibilities of occurrence and features of the course of benign nevi in men depending on the characteristics of dermatoscopic parameters

“…Although, according to scientists, the mechanism of melanoma is dominated by exogenous components [4]. The annual rate of conversion of a single nevus to is estimated at 0.0005 % or less for patients in the age group less than 40 years [17]. At the same time for a choroidal nevus this indicator makes from 2 to 3 % depending on a race [10].…”