Évaluation des facteurs biomécaniques cornéens mesurés à l’Ocular Response Analyzer dans l’hypertension intraoculaire, le glaucome primitif à angle ouvert et chez le sujet normal. Étude prospective sur 329 yeux

Streho, M.; Dariel, R.; Giraud, J.M.; Verret, Claudia; Fenolland, Jean-Rémi; Crochelet, O.; Maÿ, F.; Maurin, J. F.; Renard, Jean Paul

doi:10.1016/s0181-5512(08)74740-5

Cited by 14 publications

(5 citation statements)

References 22 publications

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“…We found that the mean and the range of the biomechanical factors CH and CRF were similar to the values reported in the literature (2). We could also confirm that, compared to normal subjects and patients with OHT, glaucomatous subjects have a significantly lower than average CH and CRF (14)(15)(16). As a hypothetical consequence, the ORA IOPcc consistently and significantly overestimated IOP compared to the applanation tonometry only in patients with glaucoma whereas the IOPcc values were only slightly but not significantly higher than the GAT values in the 2 other groups (6).…”

Section: Discussionsupporting

confidence: 89%

“…that CH may decline with advancing age, we also found that CH showed a negative correlation with age, but this correlation was only present in our group of patients with glaucoma. Streho et al (14) have reported that the values of CH would remain constant during life in patients with glaucoma, patients with OHT, as well as in normal individuals. Again, whether our findings reflect an additional factor for an increased vulnerability to glaucomatous damage with aging should be further elucidated.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Corneal Biomechanical Properties with the Reichert Ocular Response Analyzer

Detry-Morel

Jamart

Pourjavan

2010

European Journal of Ophthalmology

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Evaluation of Corneal Biomechanical Properties with the Reichert Ocular Response Analyzer

Detry-Morel

Jamart

Pourjavan

2010

European Journal of Ophthalmology

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“…Past investigations have demonstrated that IOPcc is less dependent on corneal properties than traditional contact tonometry [18,23]. Medeiros and Weinreb found that CCT was significantly correlated with GAT but not IOPcc in a population under evaluation for glaucoma.…”

Section: Discussionmentioning

confidence: 99%

“…It has been demonstrated that IOPg serves as a good approximation of GAT and may offer the clinician a tool to transition toward a corneal compensated IOP without fully abandoning GAT [17,22]. Ultimately, transitioning to a corneal compensated measure of IOP might provide the clinician with a better approximation of anterior chamber pressure, independent of corneal biomechanical properties [18,21,23,24]. …”

Section: Introductionmentioning

confidence: 99%

Goldmann applanation tonometry compared with corneal-compensated intraocular pressure in the evaluation of primary open-angle Glaucoma

2012

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BackgroundTo better understand the role of corneal properties and intraocular pressure (IOP) in the evaluation of primary open-angle glaucoma (POAG); and to determine the feasibility of identifying glaucomatous optic neuropathy (GON) using IOP corrected and uncorrected for corneal biomechanics.MethodsRecords from 1,875 eyes of consecutively evaluated new patients were reviewed. Eyes were excluded if central corneal thickness (CCT) or Ocular Response Analyzer (ORA) measurements were unavailable. Presence or absence of GON was determined based on morphology of the optic disc, rim and retinal nerve fiber layer at the time of clinical examination, fundus photography and Heidelberg Retinal Tomography. Goldmann-applanation tonometry (GAT) in the untreated state was recorded and Goldmann-correlated (IOPg) and corneal-compensated IOP (IOPcc) were obtained using the ORA. Glaucomatous eyes were classified as normal or high-tension (NTG, HTG) using the conventional cutoff of 21 mm Hg. One eligible eye was randomly selected from each patient for inclusion.ResultsA total of 357 normal, 155 HTG and 102 NTG eyes were included. Among NTG eyes, IOPcc was greater than GAT (19.8 and 14.4 mm Hg; p < 0.001) and the difference between IOPcc and GAT was greatest for this subgroup of patients with NTG (p ≤ 0.01). The maximum combined sensitivity and specificity for detection of GON occurred at 20.9 mm Hg for GAT (59%, 90%) and 18.4 mm Hg for IOPcc (85%, 85%) and the area under the curve was greater for IOPcc (0.93 vs. 0.78; p < 0.001).ConclusionsIOPcc may account for measurement error induced by corneal biomechanics. Compared to GAT, IOPcc may be a superior test in the evaluation of glaucoma but is unlikely to represent an effective diagnostic test.

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“…Streho, et al [10] came to the similar conclusions comparing intraocular pressure values obtained with the ORA tonometer (cornea compensated IOP -IOPcc and Goldmann correlated IOP -IOPg), the Goldmann tonometer and a non-contact tonometer (IOPair). Features of the cornea defined as a corneal hysteresis (CH) and a central corneal thickness, measured using ultrasound pachymetry, were analyzed additionally.…”

Section: Discussionmentioning

confidence: 54%

Decrease Corneal Hysteresis in Early Glaucoma Patients Measured with Ocular Response Analyzer (Ora) Helps in Early Diagnosis of Glaucoma

Szumny¹

2019

CTBEB

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The aim of the research was to compare the intraocular pressure value (IOP) measured with a GAT (Goldmann tonometer) with the cornea compensated IOP obtained with an ORA tonometer, and to establish whether there is a correlation between the IOP, corneal hysteresis and OCT RNFL results. Patients were divided into two groups: healthy individuals, with no ophthalmic history, and patients with early primary open angle glaucoma, treated pharmacologically with no history of either laser nor surgical eye treatment. The inclusion criteria were assessed based on the ophthalmic assessment of the optic nerve disc and perimetry (MD>-6dB). The control group included 25 subjects and the patient group 46. All measurements were performed in the Glaucoma Outpatient Clinic of the Wroclaw University Hospital: intraocular pressure with GAT and ORA, central corneal thickness, OCT RNFL. A significant positive correlation between ORA IOP and GAT IOP was found in the glaucoma group. There was significant negative correlation between ORA IOP and CH. There was a strong positive correlation between ORA IOP and GAT IOP results in the control group. Corneal hysteresis (CH) in patients with early stage glaucoma, confirmed by incorrect OCT RNFL values, is lower compared with the control group. CH is an important parameter useful for glaucoma diagnosis and evaluation of risk groups. IOP values measured with the ORA tonometer correlated with results obtained with the GAT. ORA tonometry is a novel, noninvasive method of intraocular pressure and corneal hysteresis measurement, that can be used alternatively for GAT.

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Évaluation des facteurs biomécaniques cornéens mesurés à l’Ocular Response Analyzer dans l’hypertension intraoculaire, le glaucome primitif à angle ouvert et chez le sujet normal. Étude prospective sur 329 yeux

Cited by 14 publications

References 22 publications

Evaluation of Corneal Biomechanical Properties with the Reichert Ocular Response Analyzer

Evaluation of Corneal Biomechanical Properties with the Reichert Ocular Response Analyzer

Goldmann applanation tonometry compared with corneal-compensated intraocular pressure in the evaluation of primary open-angle Glaucoma

Decrease Corneal Hysteresis in Early Glaucoma Patients Measured with Ocular Response Analyzer (Ora) Helps in Early Diagnosis of Glaucoma

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