In normal healthy eyes, the ocular pulse amplitude remains stable during normal outpatient office hours and was not correlated with blood pressure or age of patients.

Patients with glaucoma seem to have distinctive corneal biomechanical properties compared to OHT and NL. They may be influenced by many other unknown subparameters.

The combined use of the NMFu-camera and the FDP is a feasible method for an initial glaucoma mass screening. NMFu-camera may be a useful and quick method to screen for glaucomatous damage in a community. FDP in screening strategy was revealed to be not sensitive enough when setting the cut-off value at one defective test location. IOP measurements were confirmed to be a poor tool to detect glaucomatous damage.

ABSTRACT.Purpose: To compare corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer Ò tonometer (ORA) between (i) African normals and treated primary open-angle glaucoma (POAG) patients and (ii) between normals and treated POAG Caucasians. To analyse the correlation of CH and CRF with visual field (VF) defects in the two groups.Methods: This comparative study included 59 African (29 (POAG), 30 normals) and 55 Caucasians (30 POAG and 25 normals) subjects. Goldmann applanation tonometry (GAT) and ORA measurements were performed in a randomized sequence. Visual field was tested with the Swedish interactive threshold algorithms standard strategy of the Humphrey perimeter. Hoddap classification was used to estimate the severity of VF defects.Results: Primary open-angle glaucoma Africans were younger than POAG Caucasians (p < 0.001). Goldmann applanation tonometry and central corneal thickness (CCT) did not differ significantly between the four subgroups. African normals had lower CH than Caucasian controls (p < 0.001). CH was 9.2 ± 1.1 and 8.3 ± 1.7 mmHg respectively in POAG Caucasians and Africans (p < 0.001). African controls had higher ORA corneal-compensated intraocular pressure (IOPcc) than Caucasian controls (p < 0.001). Primary open-angle glaucoma Africans had higher IOPcc values than Caucasian POAGs (p < 0.001). CH and IOPcc were associated with race (p < 0.001) but not with CCT. Based on mean deviation values (MD), POAG Africans had more severe VF defects. CH was correlated with MD (r = 0.442; p = 0.031) and severity of VF defects only in POAG Africans (r = )0.464; p = 0.013).Conclusions: African normal subjects and POAG patients had an altered CH, which is associated with a significant underestimation of GAT IOP. This may potentially contribute to the earlier development and greater severity of glaucoma damage in Africans compared with Caucasians at diagnosis.

A 43-year-old man with high myopia developed unilateral pigmentary glaucoma with recurrent episodes of painless blurred vision in the left eye following uneventful phacoemulsification. Bilateral cataract surgery was performed with capsular bag implantation of a +4.00 diopter AcrySof MA60 intraocular lens (IOL) (Alcon Laboratories) followed by a neodymium:YAG laser capsulotomy. Secondary iatrogenic dispersion syndrome in the left eye with subsequent intraocular pressure elevation was suspected in the presence of anterior chamber pigmented cells, circular epithelial iris loss around the pupil, and trabecular hyperpigmentation. Close contact between the edge of the IOL and the posterior pigmented iris epithelium, which was clinically suggested by anterior biomicroscopy, was documented by ultrasound biomicroscopy and optical coherence tomography of the anterior segment.

Introduction Unilateral papillitis and neuroretinitis are uncommon manifestations of ocular Toxoplasma gondii infection and pose particularly challenging diagnosis problems. Due to the limited accessibility of healthcare and poor socioeconomic status of a significant proportion of the population in Democratic Republic of the Congo, knowledge of seroprevalence rates for toxoplasmosis remains key to the health system. When Toxoplasma papillitis or neuroretinitis is suspected, vitreous inflammatory reaction is usually present at various degrees on the initial examination as a diagnosis clue. Case report We report the case of a 37-year-old Congolese man who was managed in the University Hospital of Kinshasa, DR Congo, between October 2017 and April 2019 (18 months). The patient's informed consent was obtained for publication of his data. The patient developed presumed Toxoplasma papillitis with complete absence of vitritis at presentation. He was in good general health and had a known contact with a cat. Ophthalmoscopic examination revealed unilateral inflammation in the left optic disc and peripapillary area coexisting with active juxtapapillary retinochoroiditis that could be confirmed in ocular coherence tomography. A retinochoroiditis scar was present in the right eye. Left visual field was severely altered in automated perimetry. Toxoplasma titer was positive. Anti-HIV (ELISA) antibodies were negative. Rapid and favorable response to appropriate antiparasitic agents was observed without recurrence. Absence of vitritis and retinochoroiditis scar were confirmed during all the follow-up period. Conclusions Papillary toxoplasmosis is rare and potentially serious. Its diagnosis must be sought, even in the absence of vitritis, before taking into account any unilateral papillary edema. Our case report highlights the importance of detailed history and clinical examination to improve diagnostic decision making such as the need for complementary investigations, especially serologic testing, in a country with relatively limited financial resources in public health.

No abstract

Self-inflicted optic nerve injury should be included in the differential diagnosis of progressive optic neuropathy in a young adult.