Évaluation de l’activité anti-inflammatoire et screening phytochimique des feuilles de Annona senegalensis

Yeo, Dodehe; Dinică, Rodica Mihaela; Yapi, H F; Furdui, Bianca; Praisler, Mirela; Djaman, Allico Joseph; N’Guessan, Jean David

doi:10.2515/therapie/2010076

Cited by 20 publications

(11 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results are in agreement with those obtained by Konaté et al [12], with the aqueous extract of the root bark of this plant. On the other hand, studies by Yéo et al [20] did not reveal the presence of alkaloids and quinone compounds in the ethanolic extract of the leaves of Annona senegalensis.…”

Section: Discussionmentioning

confidence: 93%

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Nanti¹,

Bi²,

Zahoui³

et al. 2018

J Intercult Ethnopharmacol

View full text Add to dashboard Cite

Aim: In order to promote African traditional pharmacopoeia, studies have been undertaken to evaluate the effects of aqueous extracts of Annona senegalensis (Annonaceae) (EAAs) and Hallea ledermannii (Rubiaceae) (EAHl) in white rats of Wistar strain. Methods: A phytochemical screening and a toxicological study according to the Organisation for Economic Co-operation and Development guidelines 423 were carried out. Pharmacological effects on blood glucose were evaluated. The different treatments were performed orally. Results:The aqueous extracts of EAAs and EAHl, respectively, at the maximum doses of 3,000 and 5,000 mg/kg bw, did not cause death in rats. Phytochemical screening revealed the presence of polyphenols, flavonoids, and quinonic compounds in both extracts. This study showed that in addition to the common compounds, the Annona senegalensis extract contained sterols, polyterpenes, catechic tannins, and alkaloids, while that of Hallea ledermannii showed the existence of saponosides. Annona senegalensis (100 mg/kg bw) and Hallea ledermannii (200 mg/kg bw), provoked more hypoglycemia, respectively, of 40% and 35.34% in rats. EAAS (27.78% vs. 25.41%) showed better anti-hyperglycemic effect in pretreated rats while EAHl (40.30% vs. 29.37%), provoked more anti-hyperglycemic activity in post-treated animals. Conclusion:The effects of EAAs and EAHI on blood glucose value may be related to the presence of chemical compounds such as flavonoids and saponosides highlighted in a phytochemical study. These compounds recall those of certain insulin-secreting agents and justify their use in traditional medicine. ARTICLE HISTORY

show abstract

Section: Discussionmentioning

confidence: 93%

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Nanti¹,

Bi²,

Zahoui³

et al. 2018

J Intercult Ethnopharmacol

View full text Add to dashboard Cite

show abstract

“…The increase in the percentage of inhibition observed with the ethanolic extract of these plant extracts is due to the increase in the number of inflammatory cells including mast cells, neutrophils cells and macrophages cells. In addition, flavonoids decrease the permeability of blood capillaries and make them more resistant [47]. The results of this previous work have shown that flavonoids and phenolic compounds including coumarins possess anti-inflammatory properties [48].…”

Section: Discussionmentioning

confidence: 97%

Phenolic Profile and Antioxidant, Anti-Inflammatory Activity of <i>Annona senegalensis, Ipomoea batatas, Terminalia superba</i> and <i>Psidium guajava</i> Linn Extracts Used in Benin

Irène¹,

Eugenie²,

Durand³

et al. 2022

AJPS

View full text Add to dashboard Cite

The purpose of this study is to quantify the polyphenolic content and evaluated anti-inflammatory and antioxidant activity of four plants extracts of Annona senegalensis, Ipomoea batatas, Terminalia superba and Psidium guajava. Phenolic and flavonoid contents were determined by Folin-Ciocalteu and aluminum trichloride methods, respectively with ethanolic extract. The antioxidant activity was accessed by DPPH and FRAP methods. The results of the analysis of this study indicate that the ethanol extracts of the test plants (A. senegalensis, I. batatas, P. guajava and T. superba) are potential source of natural antioxidant and anti-inflammatory.

show abstract

“…Previous studies have shown that polyphenols, in particular flavonoids, can mediate interactions with the phospholipidic cytoplasmic membrane, thereby reducing fluidity and enhancing rigidity [ 59 , 62 ]. These interactions protect the membrane from harmful substances, thus ensuring the physiological function and integrity of the membrane [ 63 ]. Several studies have reported that plant-derived flavonoids have anti-inflammatory properties [ 59 , 64 ].…”

Section: Discussionmentioning

confidence: 99%

Exploration of the Antioxidant and Anti-inflammatory Potential of Cassia sieberiana DC and Piliostigma thonningii (Schumach.) Milne-Redh, Traditionally Used in the Treatment of Hepatitis in the Hauts-Bassins Region of Burkina Faso

et al. 2023

View full text Add to dashboard Cite

Inflammation is the supreme biological response to illness. In the Hauts-Bassins region, in traditional medicine, all parts of Cassia sieberiana and Piliostigma thonningii are used to treat hepatitis and inflammation. The aim of this study was to evaluate the in vitro antioxidant and anti-inflammatory activities of their aqueous extracts. High performance liquid chromatography with photodiode array (HPLC-DAD) and ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-MS/MS) analyses highlighted the presence of polyphenols and flavonoids. Antioxidant and anti-inflammatory activities were measured by various methods such as DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), TAC (total antioxidant capacity), anti-protease, anti-lipoxygenase, and membrane stabilization. The best antioxidant activity was observed in the bark (DPPH: IC50 = 13.45 ± 0.10µg/mL) and roots (TAC = 29.68 ± 1.48 mgAAE/g DW) of Piliostigma thonningii and in the roots (ABTS: IC50 = 1.83 ± 0.34 µg/mL) of Cassia sieberiana. The best anti-inflammatory activity was observed in the bark (anti-lipoxygenase: IC50 = 13.04 ± 1.99 µg/mL) and leaves (anti-proteases: IC50 = 75.74 ± 1.07 µg/mL, membrane stabilization: IC50 = 48.32 ± 6.39 µg/mL) of Cassia sieberiana. Total polyphenols (ABTS: r = −0.679, TAC: r = 0.960) and condensed tannins (ABTS: r = −0.702, TAC: r = 0.701) were strongly correlated with antioxidant activity. Total flavonoids (anti-proteases: r = −0.729), condensed tannins (anti-proteases: r = 0.698), and vitamin C (anti-proteases: r = −0.953) were strongly correlated with anti-inflammatory activity. Total polyphenols, flavonoids, condensed tannins, and vitamin C could contribute to the antioxidant and anti-inflammatory activities of the two studied plants. These results could validate the traditional use of these plants to treat various inflammatory diseases.

show abstract

Évaluation de l’activité anti-inflammatoire et screening phytochimique des feuilles de Annona senegalensis

Cited by 20 publications

References 18 publications

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Phenolic Profile and Antioxidant, Anti-Inflammatory Activity of <i>Annona senegalensis, Ipomoea batatas, Terminalia superba</i> and <i>Psidium guajava</i> Linn Extracts Used in Benin

Exploration of the Antioxidant and Anti-inflammatory Potential of Cassia sieberiana DC and Piliostigma thonningii (Schumach.) Milne-Redh, Traditionally Used in the Treatment of Hepatitis in the Hauts-Bassins Region of Burkina Faso

Contact Info

Product

Resources

About

Évaluation de l’activité anti-inflammatoire et screening phytochimique des feuilles de Annona senegalensis

Cited by 20 publications

References 18 publications

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Comparative study of Annona senegalensis (Annonaceae) and Hallea ledermannii (Rubiacaceae) effects on glycemia in rats

Phenolic Profile and Antioxidant, Anti-Inflammatory Activity of &lt;i&gt;Annona senegalensis, Ipomoea batatas, Terminalia superba&lt;/i&gt; and &lt;i&gt;Psidium guajava&lt;/i&gt; Linn Extracts Used in Benin

Exploration of the Antioxidant and Anti-inflammatory Potential of Cassia sieberiana DC and Piliostigma thonningii (Schumach.) Milne-Redh, Traditionally Used in the Treatment of Hepatitis in the Hauts-Bassins Region of Burkina Faso

Contact Info

Product

Resources

About

Phenolic Profile and Antioxidant, Anti-Inflammatory Activity of <i>Annona senegalensis, Ipomoea batatas, Terminalia superba</i> and <i>Psidium guajava</i> Linn Extracts Used in Benin