2020
DOI: 10.21608/omx.2020.39319.1081
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Evaluation and Comparison of Histologic Changes in Extraction Sites Grafted with Simvastatin mixed with Nanobone

Abstract: Objective:The objective of the present study was to compare the effect of mixing simvastatin with Nanobone graft on the healing process of extraction sockets regarding to the histological parameter. Materials and Methods: In a prospective randomized clinical study, ten patients (study group, Group II) treated by simvastatin mixed with Nanobone after tooth extraction. The other ten patients (Control group, Group I) received Nanobone only. Three months after tooth extraction and socket preservation, histological… Show more

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“…Because of their smaller size, nanoparticles are more utilized by the body than free one and more effective in antibacterial and antifungal activity (Sahlan et al, 2017;Afrouzan et al, 2012). NanoBone graft material is a newly created and authorized granular material for bone regeneration that is made up of synthetic nanocrystalline hydroxy-appatite embedded in a silica gel matrix that mimics the structure of normal bone tissue (Soliman et al, 2020). Nanobone and propolis in combination produced better effects than nanobone alone.…”
Section: Figurementioning
confidence: 99%
“…Because of their smaller size, nanoparticles are more utilized by the body than free one and more effective in antibacterial and antifungal activity (Sahlan et al, 2017;Afrouzan et al, 2012). NanoBone graft material is a newly created and authorized granular material for bone regeneration that is made up of synthetic nanocrystalline hydroxy-appatite embedded in a silica gel matrix that mimics the structure of normal bone tissue (Soliman et al, 2020). Nanobone and propolis in combination produced better effects than nanobone alone.…”
Section: Figurementioning
confidence: 99%