Evaluating the effectiveness of prophylactic central neck dissection with total thyroidectomy for cN0 papillary thyroid carcinoma: An updated meta-analysis

Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

“…The use of prophylactic central neck dissection for low-risk tumours (T1b-T2, N0) varies from centre to centre [IV, C] [37][38][39]. Evidence of its effect on recurrence-free survival is conflicting, and there is no high-level evidence for or against its usefulness for low-risk tumours.…”

The Effect of Prophylactic Central Neck Dissection During Hemithyroidectomy on Locoregional Recurrence in Patients With Papillary Thyroid Carcinoma: A Meta-Analysis

“…However, controversy regarding central neck dissection persists, even in cases of hemithyroidectomy, given that occult nodal metastasis in the central compartment has been observed in approximately one-half of patients clinically diagnosed with N0 papillary carcinoma [3,4]. Some meta-analyses have investigated the effectiveness of prophylactic central neck dissection performed with total thyroidectomy [5][6][7], but not in patients undergoing hemithyroidectomy alone. The purpose of this study, therefore, was to evaluate the oncological effect of prophylactic central neck dissection performed during hemithyroidectomy in patients with low-to intermediate-risk papillary thyroid carcinoma.…”

The learning curve of endoscopic thyroid surgery for papillary thyroid microcarcinoma: CUSUM analysis of a single surgeon’s experience

“…The key and difficult points for CND were ensuring sufficient dissection and avoid additional damage. Previous studies indicate that CND led to 12.1% increase in the temporary hypoparathyroidism rate with a 1.7% increased rate for permanent hypoparathyroidism and 1.3% for temporal RLN, which would impair quality of life [20]. Although there was rare hypoparathyroidism in hemithyroidectomy with CND because of bilateral PTGs, it demanded us to more carefully dissect RLN and PTGs.…”