Evaluating response to mood stabilizers in patients with mixed depression: A study of agreement between three different mania rating scales and a depression rating scale

<p>Effects of Lithium Combined with Second-Generation Antipsychotics for the Treatment of Manic Episodes in Patients with Bipolar Disorder: A Naturalistic Study in China</p>

“…Research indicates that BRMS and YMRS are quite consistent, both compared mania scales revealed satisfactory indices of reliability and validity. 28 , 29 Bech-Rafaelsen Mania Scale has been used extensively in trials that have assessed the efficacy of treatments for bipolar disorder. 30 In this study, all patients were rated using BRMS by two experienced doctors on admission.…”

Measures of the DSM–5 mixed-features specifier of major depressive disorder

“…There are several clinician-rated measures of the severity of manic symptoms. The content of these scales overlap, thereby resulting in significant correlations between them, 51 though there are also meaningful differences that can result in different response rates in bipolar depressed patients with mixed features 52 . The scales also differ with respect to the timeframe of the assessment.…”

The Koukopoulos mixed depression rating scale (KMDRS) and the assessment of mixed symptoms during the perinatal period

“…Mixed states were first described by Emil Kraepelin (1899) and his pupil Wilhelm Weygandt (1899). However, the classical dichotomization of psychiatric disorders into neurotic and psychotic disorders relegated mood disorders to the former, and contributed to the neglect where MxD was cast, until the last version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) (Prieto et al, 2015;Shansis et al, 2016), where MxD was defined as consisting of a MDE with at least three concurrent (hypo)manic symptoms (American Psychiatric Association, 2013). However, controversy over the mixed state concept is still ongoing (Perugi et al, 2015;Maj, 2015;Goldberg, 2015).…”