Euterpe olerácea (açaı̧) as an alternative oral contrast agent in MRI of the gastrointestinal system: preliminary results

Córdova–Fraga, Teodoro; Araújo, Dráulio Barros de; Sanchez, Tiago Arruda; Elias, Jorge; Carneiro, Adriana Munhoz; Brandt-Oliveira, R.; Sosa, M.; Baffa, Oswaldo

doi:10.1016/j.mri.2004.01.018

Cited by 32 publications

(33 citation statements)

References 19 publications

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“…The oral contrast agent used in magnetic resonance imaging and the vasodilator effect have been reported (Córdova-Fraga et al, 2004;Rocha et al, 2007). Ribeiro et al (2010) also observed that açaí pulp was not genotoxic in mouse bone marrow or liver and kidney cells and plays a role in inhibiting the genotoxicity induced by the antitumoral agent DXR.…”

Section: Introductionmentioning

confidence: 99%

Multiple emulsions containing amazon oil: açaí oil (Euterpe oleracea)

Ferrari¹,

Rocha‐Filho

2011

Rev. bras. farmacogn.

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Abstract:The aim of this work was to formulate O/W/O multiple emulsions containing açaí oil as a model system and to evaluate their physical stability and in vivo Sun Protection Factor (SPF). Multiple emulsions are complex dispersion systems, known also as, "emulsions of emulsions". These emulsion systems, have significant potential in the cosmetic industry. Euterpe oleracea Mart., Arecaceae, popularly known in Brazil as "açaí", is an economically important plant. Açaí oil has been used as antioxidant and as anti-inflammatory activities. The multiple emulsions were prepared using a two-step procedure. The investigated formulations were characterized and their stability over time was evaluated by preliminary and accelerated stability. O/W/O multiple emulsions containing the same concentration of sunscreens with and without açaí oil were evaluated by the International Sun Protection Factor Test Method. The samples containing 70% (w/w) of primary emulsion, 5% (w/w) PEG-30-dipolyhydroxystearate, 10% (w/w) of açaí oil and 5% (w/w) of sucrose polybehenate have been found to be stable. The rheological measurements revealed that the samples exhibited non-Newtonian pseudoplastic flow behavior and thixotropy. To conclude, no statistical difference could be observed on the in vivo SPF to both multiple systems with or without açaí oil.

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Section: Introductionmentioning

confidence: 99%

Multiple emulsions containing amazon oil: açaí oil (Euterpe oleracea)

Ferrari¹,

Rocha‐Filho

2011

Rev. bras. farmacogn.

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“…Several studies have used contrast agents to suppress the signal of the digestive tube [20][21][22]. The ideal oral contrast agent for MR should have a good acceptance by patients, have a uniform distribution in the lumen of the digestive tract, should not be diluted during its trajectory, should not be toxic, should not stimulate peristalsis, and should have an acceptable cost [21].…”

Section: Introductionmentioning

confidence: 99%

Use of pineapple juice with gadopentetate dimeglumine as a negative oral contrast for magnetic resonance cholangiopancreatography: a multicentric study

2011

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We evaluated the efficacy of pineapple juice with gadopentetate dimeglumine as a negative oral contrast agent for magnetic resonance cholangiopancreatography (MRCP). Images were obtained before and after the intake of a negative oral contrast agent. Images obtained from six different areas of the biliary tree were analyzed by three different radiologists, who were blind to the exams; scores regarding image quality were given to each area. The statistical analysis showed a significant difference between images before and after the use of the contrast agent (P < 0.001) for the three radiologists (R1-R3). Mean scores given by radiologists before the intake of the contrast agent were 2.49 ± 0.42 (R1), 2.62 ± 0.32 (R2), and 2.22 ± 0.46 (R3). After the intake, mean scores were 3.38 ± 0.62 (R1), 3.48 ± 0.55 (R2), and 2.89 ± 0.69 (R3). The ducts that showed the highest scores were the common bile duct and duct of Wirsung, the distal portion of the common bile duct and the cystic duct. We suggest herein that the contrast agent pineapple juice with gadopentate dimeglumine constitutes an efficient negative oral contrast agent for MRCP, for it efficiently eliminates the signal of the digestive tube in MRCP images.

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“…It also presents ornamental potential [17,18], in view of its morphological aspects. Highlights the therapeutic use [19]; The medicinal use [20]; Food use [21,22];Bioenergetic potential [23];High antioxidant activity [24,25,26].…”

Section: Usesmentioning

confidence: 99%