Eudesmane sesquiterpenoid lactones and abietane diterpenoids from Ajuga forrestii Diels

Diterpenoids from Saliva plebeia R. Br. and Their Antioxidant and Anti-Inflammatory Activities

“…Key HMBC correlations were given in Figure 2. According to these, the structure 1 , similar to the structure of 2α,3β,11,12-tetrahydroxy-7β,20-epoxy-8,11, 13-abietatriene [10], was established basically. The difference between the two compounds is that the ether bond does not exist in compound 1, along with the different locations of isopropyl and phenolic hydroxyls.…”

“…By comparing the spectral data (MS, 1 H-NMR, 13 C-NMR) with the reported values, four known diterpenoids were identified as carnosol ( 2 ) [11], isocarnosol ( 3 ) [12], saficinolide ( 4 ) [13] and 2,11,12-trihydroxy-7,20-epoxy-8,11,13-abietatriene ( 5 ) [10].…”

Stereocontrolled Synthesis and Structural Revision of Plebeianiol A

“…In an unusual twist, the authors proposed the presence of an isopropyl group on the B ring at C7 and a phenolic hydroxyl group in the location typical of the abietane isopropyl group at C13. Whereas the authors noted that this proposal was unusual given the typical structures of abietane natural products (see 1 – 3 ) and the coisolation of plebeianiol A with carnosol and other “normal” abietanes, they nonetheless proposed a highly unusual biogenesis of this compound. − Additionally, the absolute configuration at C10 was designated as R even though all documented aromatic abietanes have been assigned S configurations at this position. On these grounds and after careful re-examination of the NMR spectral data disclosed for plebeianiol A, we were led to conclude that the structure had likely been misassigned and might, in fact, be 5 , with the typical features of an abietane diterpenoid.…”

Characterization of the complete chloroplast genome of Ajuga forrestii (Lamiaceae), a medicinal plant in southwest of China

“…Among these species, Ajuga forrestii is widely distributed in southwest China which have been used in local medicine as anti-inflammatory, antioxidant, cytotoxic, analgesic, or antibacterial activity (Toiu et al 2018). However, up to now for such medicinal plant, many studies have mainly focused on describing its chemical compositions (Wang et al 1994;Xiong et al 2013;Chen et al 2018), with little involvement in its molecular biology, so that no comprehensive genomic resource is conducted for it. Here, we report the chloroplast genome sequence of A. forrestii and find its internal relationships within the family Lamiaceae.…”

“…1994 ; Xiong et al. 2013 ; Chen et al. 2018 ), with little involvement in its molecular biology, so that no comprehensive genomic resource is conducted for it.…”