2015
DOI: 10.3390/molecules200814879
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Diterpenoids from Saliva plebeia R. Br. and Their Antioxidant and Anti-Inflammatory Activities

Abstract: Abstract:A new skeleton of diterpenoid, 1,2,3,4,4α,9,10,10α-octahydro-(4α-hydroxyymethyl) -1,1-dimethyl-9-(1-methylethyl)-(2S,3S,4αR,9R,10αS)-2,3,5,7-phenanthrenetertrol, named plebeianiol A (1), along with four known diterpenoids (2-5), were isolated from Salvia plebeia R. Br. Their structures were determined on the basis of spectral analysis. In the bioactivity tests, compounds 1, 2 and 5 showed 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities with IC50 values of 20.0-29.6 µM. In addition, … Show more

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Cited by 22 publications
(26 citation statements)
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“…Eudesmane‐12,8‐lactams were extremely rare in nature, being described so far only few such compound had been obtained from Curcuma phaeocaulis . Meanwhile, only a few eudesmane‐12,8‐olides were reported from the genus of Salvia . This work revealed the existence of eudesmane‐12,8‐lactam from Salvia genus for the first time.…”
Section: Resultsmentioning
confidence: 68%
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“…Eudesmane‐12,8‐lactams were extremely rare in nature, being described so far only few such compound had been obtained from Curcuma phaeocaulis . Meanwhile, only a few eudesmane‐12,8‐olides were reported from the genus of Salvia . This work revealed the existence of eudesmane‐12,8‐lactam from Salvia genus for the first time.…”
Section: Resultsmentioning
confidence: 68%
“…[16] Meanwhile, only a few eudesmane-12,8-olides were reported from the genus of Salvia. [9][12] [13] [17] This work revealed the existence of eudesmane-12,8-lactam from Salvia genus for the first time. Compounds 1 -3 were tested for antiproliferative activities against myeloid leukemia cell lines K562, U937, and oci-ly1.…”
Section: Resultsmentioning
confidence: 95%
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