Etude histo-pathologique de la dermatite périorale

Abstract

38 biopsies of perioral dermatitis have been examined. The following has consistently been observed: follicular hyperkeratosis; vasodilatation and oedema (sometimes very pronounced) of the papillary dermis; peri vascular and parafollicular infiltrates consisting predominantly of lymphocytes, histiocytes and polymorphonuclear leucocytes. Occasionally, there have been epithelioid or giant cells, sarcoid-like infiltrates or vasculitis of the leucoclastic type. Demodexfolliculorum was observed in only two sections and the follicles that contained them were not inflamed. This histological picture is very similar to that of acne rosacea.

Epithelial barrier function and atopic diathesis in rosacea and perioral dermatitis

“…Nevertheless, the pathogenesis of both diseases remains enigmatic. Due to clinical and histological similarities it is still disputed whether PD is a subtype of rosacea or is an individual clinical entity 18–21 . Similarly to a former investigation, the present study has shown that patients with PD are often atopic.…”

“…The clinical pattern can be quite similar, especially in forms of PD that spare the perioral region 19 . Some authors have stated that the diseases may be indistinguishable with regard to histology, 20,21 while others maintain that the histological picture of PD differs somewhat from that of rosacea 18 . There are similar granulomatous variants of both diseases, and both are aggravated by topical corticosteroids 16,17 , 20,21 .…”

Granulomatous Perioral Dermatitis in Children

“…When it does occur in children under 15 A distinctive form of sarcoidosis, consisting of arthritis, uveitis, and multiple, closely spaced pap¬ ules located on the flexor surfaces of the arms and legs, has been reported in very young children. When it does occur in children under 15 A distinctive form of sarcoidosis, consisting of arthritis, uveitis, and multiple, closely spaced pap¬ ules located on the flexor surfaces of the arms and legs, has been reported in very young children.…”