Etude Ethnobotanique des plantes médicinales utilisées dans le traitement traditionnel des hépatites virales B et C dans quelques départements du Bénin

Guinnin, Fdf; Sacramento, TI; Sèzan, Alphonse; Ategbo, J-M

doi:10.4314/ijbcs.v9i3.20

Cited by 25 publications

(38 citation statements)

References 6 publications

(2 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Buruli ulcer (Tsouh Fokou et al, 2015); viral hepatitis A and C (Guinnin et al, 2015) ; liver damage (Sangare et al, Not toxicity effect (Adlin Afzan et al, 2012); no significant toxic effect of the oral administration of the aqueous extract of leaves (Ismail et al, 2014) 2012a); dysentery, diabetes, constipation and chronic indigestion (Khan et al, 2015). Cochlospermum tinctorium Perr.…”

Section: Senna Occidentalis (L) Linkmentioning

confidence: 97%

“…Oral administration of extract yielded LD 50 ≥ 5000 mg / kg body weight a significant increase in transaminases at this dose (Abou et al, 2015) Effects of aqueous extract on liver enzymes (Sangare et al, 2012b). Viral hepatitis A and C (Guinnin et al, 2015); liver damage (Sangare et al, 2012a); diarrhea (Rakotoarivelo et al, 2015); skin diseases (Khan et al, 2015) ; toothache (Malan et al, 2015). LD 50 of 2.30 g/kg in acute toxicity tests in rabbits with aqueous extract of husk fiber (Alviano et al, 2004); no acute lethal effects in mice .…”

Section: Plant Parts Used Modes Of Preparation and Administration Romentioning

confidence: 97%

“…Hepatoprotective activity of the nut water on carbon tetrachloride induced liver injury in rats (Loki and Rajamohan, 2003 (Guinnin et al, 2015) ; liver damage (Sangare et al, 2012a) ; swollen breasts (Malan et al, 2015); sexually transmitted infections (Naidoo et al, 2013).…”

Section: Plant Parts Used Modes Of Preparation and Administration Romentioning

confidence: 97%

“…Viral hepatitis A and C (Guinnin et al, 2015); liver damage (Sangare et al, 2012a) Cytotoxicity of the hydroalcoholic extract of aerial parts found in mouse fibroblasts. (Lombardo et al, 2015); Sub acute toxicity of seeds in rats ( Barbosa-Ferreira et al, 2005); acute and subacute toxicities of ethanolic extract of leaves (Pieme et al, 2005).…”

Section: Senna Occidentalis (L) Linkmentioning

confidence: 98%

See 3 more Smart Citations

An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo

Kpodar

Karou

Katawa

et al. 2016

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Section: Senna Occidentalis (L) Linkmentioning

confidence: 97%

Section: Plant Parts Used Modes Of Preparation and Administration Romentioning

confidence: 97%

Section: Plant Parts Used Modes Of Preparation and Administration Romentioning

confidence: 97%

Section: Senna Occidentalis (L) Linkmentioning

confidence: 98%

See 2 more Smart Citations

An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo

Kpodar

Karou

Katawa

et al. 2016

Journal of Ethnopharmacology

View full text Add to dashboard Cite

“…They are most often caused by viruses, but also by toxic substances, alcohol and certain drugs [1]. A. albida Duch is a recurrent plant used in the treatment of viral hepatitis B and C in Benin [2]. It is of the branch of the Magnoliophyta and the great family of the Aristolochiaceae, [3].…”

Section: Introductionmentioning

confidence: 99%

Acute Toxicity Evaluation of Ethanolic Extract of Aristolochia Albida Duch. Leaves on Wistar Rats Liver and Kidney Functions

Guinnin

Klotoé

Atègbo

2017

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

Objective: Aristolochia albida Duch is frequently used by alternative medicine to treat some pathologies like hepatitis. Our main objective was to evaluate the acute oral toxicity of the ethanolic extract of this plant.Methods: Exploratory tests for acute oral toxicity are performed in vivo on Wistar albino rats in a limit test of 2000 mg/kg for 14 d in accordance with the OECD Guidelines 423. The clinical signs were observed every day, followed by measurement of body weight change, the haematological and biochemical examinations were executed and statistical analysis was performed. Results:The various clinical signs observed after administration and for 14 d were recorded and no mortality was observed. With the exception of white blood cells, mean cell volume and platelets with statistically significant difference in control (p<0.05), all the haematological parameters showed an insignificant statistical difference to the control ratio (p>0.05). For biochemical parameters, except blood glucose and total protein of control batches, which show a significant statistical difference after 14 d (p>0.05), all the biochemical parameters show the statistically insignificant difference for test and controls batches (p>0.05) as well as the weight variation of the animals. Conclusion:The ethanolic extract of the leaves of A. albida Duch (EEAr) had not toxic effect on the biochemical and hematological parameters studied at a dose of 2000 mg/kg. The lethal dose is therefore over 2000 mg/kg.

show abstract

Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses

Sut,

Dall'Acqua,

Sinan

et al. 2024

J Sci Food Agric

View full text Add to dashboard Cite

BackgroundParkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to study their phytochemical contents, antioxidant, and enzyme inhibitory properties.ResultsLC‐QTOF‐MS and LC‐MSn revealed the presence of flavonoids, hydroxycinnamic acid derivatives and gallotannins. Particularly, the water extract contained rutin (480 μg/100 mg) and 3‐caffeoylquinic acid (1109 μg/100 mg) in higher amounts, while the 80% methanol extract contains methoxyluteolin‐7‐O‐rutinoside and catechin derivatives as major compounds. Total phenolic and flavonoid contents of the extracts were yielded in the range of 32.26‐119.88 mg GAE/g and 0.60‐2.39 mg RE/g, respectively. Total antioxidant capacity was also displayed in the range of 0.53‐6.34 mmol TE/g. Both the methanolic extracts showed higher total antioxidant capacity which could be related to the total phenolic contents. Radical scavenging capacity in DPPH (37.21‐508.30 mg TE/g) and ABTS (60.95‐1068.06 mg TE/g) assays, reducing power in CUPRAC (54.23‐1002.78 mg TE/g) and FRAP (33.18‐558.68 mg TE/g) assays as well as metal chelating activity (2.45‐11.28 mg EDTAE/g) were exhibited by all extracts. All extracts were found to inhibit acetylcholinesterase (0.23‐2.47 mg GALAE/g), tyrosinase (27.20‐83.33 mg KAE/g), amylase (mmol ACAE/g). On the other hand, all extracts except the water extract, inhibited butyrylcholinesterase (5.38‐6.56 mg GALAE/g), while only the water and ethyl acetate extract showed glucosidase inhibitory potential (1.96 and 1.82 mmol ACAE/g). In general, the water extract was found to be a weaker enzyme inhibitor suggesting that water is not the preferrable extraction solvent to obtain active products.ConclusionThis study demonstrated that the stem bark extracts of P. biglobosa contains good amount of phytochemical and extracts present significant antioxidant as well as reasonable enzyme inhibitory effects. Hence, these findings suggest that further studies can be performed on more specific biological targets and models of bioactivity to determine their safe usage as a nutraceutical or for the preparation functional foods.This article is protected by copyright. All rights reserved.

show abstract

Etude Ethnobotanique des plantes médicinales utilisées dans le traitement traditionnel des hépatites virales B et C dans quelques départements du Bénin

Cited by 25 publications

References 6 publications

An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo

An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo

Acute Toxicity Evaluation of Ethanolic Extract of Aristolochia Albida Duch. Leaves on Wistar Rats Liver and Kidney Functions

Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses

Contact Info

Product

Resources

About