Etiologic and differential diagnostic significance of tumor location in the supraclavicular fossa

Franzen, Achim; Günzel, Thomas; Buchali, A.; Coordes, Annekatrin

doi:10.1002/lary.26775

Cited by 17 publications

(9 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since the cranial nerves and laryngeal nerves are associated with pouch derivatives, it does not seem far-fetched that an isolated tumor may develop in an unusual location like the posterior axilla. Clinically, the vast majority of supraclavicular masses represent metastatic tumors or lymphoma, with the majority of tumors primary carcinomas below the clavicles, with genitourinary primaries affecting the left side disproportionately [41]. If we classify "suprasternal" and "presternal" as "midline", the ratio of left-sided : midline : right-sided is 35 (51%):17 (25%):16 (24%) (n = 68).…”

Section: Discussionmentioning

confidence: 99%

Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma

Sato

Thompson

Miyai

et al. 2017

Head and Neck Pathol

View full text Add to dashboard Cite

Ectopic hamartomatous thymoma (EHT) is a rare benign neoplasm of the lower neck suggesting branchial origin. Despite use of the term thymoma in the nomenclature, there is no evidence of thymic origin or differentiation. It affects middle-aged adults with a remarkable male predominance. To date less than 80 cases have been reported in the English literature. We present here two additional cases of EHT. The first is a benign case in a 31-year-old man, showing typical histological features. The second is a malignant case in a 70-year-old woman, showing intraductal carcinoma arising in intimate association with an EHT. These cases are presented in the context of a review of cases reported in the English literature. The exact origin has not been identified, but is considered to be of branchial apparatus, creating a quandary about the best terminology. Recently, the designation "branchial anlage mixed tumor" or "thymic anlage tumor" were proposed, but do not quite reflect the true nature of the neoplasm. To avoid taxonomic confusion, international consensus on terminology is desired. As this entity is a neoplasm that shows dual mesoderm and endoderm derivation/differentiation, we propose a new name "biphenotypic branchioma."

show abstract

Section: Discussionmentioning

confidence: 99%

Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma

Sato

Thompson

Miyai

et al. 2017

Head and Neck Pathol

View full text Add to dashboard Cite

show abstract

“…Even malignant lymphoma may present as a cystic lesion. Cystic metastases from a primary tumor below the clavicle remain rare exceptions (17). In 15 patients with a histological diagnosis of SCC, no primary tumor was found, even after a meticulous search.…”

Section: Discussionmentioning

confidence: 99%

Cystic Lateral Neck Lesions: Etiologic and Differential Diagnostic Significance in a Series of 133 Patients

Franzen

Günzel²,

Buchali

et al. 2019

Anticancer Res

Self Cite

View full text Add to dashboard Cite

Background: Patients presenting with a cystic lateral neck lesion may present diagnostic challenges against a backdrop of varied non-malignant and malignant etiologies. Patients: A total of 133 consecutive cases who underwent cystic neck tumor removal were evaluated for etiology and diagnostic procedure in order to develop an algorithm for therapeutic efficiency. Results: In 92 of 133 cases, a non-malignant tumor was diagnosed. In 41 cases, malignant lymphadenopathy was found. In cases with malignancy, males (p=0.001) and the elderly (p=0.001) were affected more frequently. Primary tumors were discovered by pan-endoscopy before neck surgery or in a second panendoscopy (with tonsillectomy and mapping biopsies) in cases with histologically confirmed squamous cell carcinoma. During intraoperative frozen-section evaluation (40 cases), a total of 30 patients underwent neck dissection during the first neck operation. Conclusion: In patients older than 40 years who present with cystic neck lesions, we recommend pan-endoscopy and intraoperative frozen section in cases where malignancy is suspected in order to avoid secondary neck dissections and delays in therapy.A cystic lesion of the lateral neck is a relatively rare occurrence for an Ear, Nose and Throat (ENT) specialist. The majority of cases are interpreted as branchial cleft cysts that arise from the second branchial arch and become symptomatic in children and younger adults (1). On the other hand, there are a wide variety of neck mass etiologies including congenital, local or systemic inflammatory, benign and malignant causes (2). Cystic metastases may represent a unique entity with different etiological features such as a lack of exposure to risk factors and presentation in younger or female patients. Patient age may be an independent predictive factor for malignancy (2, 3). In this way, a cystic neck lesion may represent a cystic metastasis of squamous cell carcinoma (SCC) from the head and neck, particularly in human papillomavirus-related carcinoma of Waldeyer's ring (4). However, cystic metastases should be separated from central necrosis following rapid tumor growth (5). Branchial cleft cyst carcinoma has long been a subject of discussion (6,7).This study investigated the data of patients who were admitted to the ENT Department by an ENT practitioner and diagnosed with a "branchial cleft cyst" requiring surgical treatment. The objective of the present study was to evaluate the significance of a cystic cervical mass in relation to etiology, diagnostic procedure and an algorithm for increased therapeutic efficiency.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Neoplastic adenopathy at Virchow's node is a well-known indicator of abdominal malignancy [ 7 ]. However, duodenal adenocarcinoma is a rare cause and accounts for less than 0.5% of gastrointestinal malignancies [ 7 , 8 ]. Duodenal adenocarcinoma may also present with epigastric pain, gastric outlet obstruction, jaundice, cholangitis, melena, anemia, abdominal mass, and weight loss, or it may be incidental finding in asymptomatic patients [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome

Nadeau

Brule

2018

Case Reports in Genetics

View full text Add to dashboard Cite

Rothmund-Thomson syndrome is a genetic disorder with characteristic findings in childhood as well as a predisposition to osteosarcoma, skin cancer, and hematological malignancy. We present the first reported case of duodenal malignancy in a patient with Rothmund-Thompson syndrome. An enlarged Virchow's node was noted and an advanced duodenal adenocarcinoma was diagnosed shortly thereafter. The features of Rothmund-Thomson syndrome are discussed, as well as current management and screening guidelines for duodenal adenocarcinoma.

show abstract

Etiologic and differential diagnostic significance of tumor location in the supraclavicular fossa

Abstract: 4. Laryngoscope, 128:646-650, 2018.

Cited by 17 publications

References 24 publications

Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma

Ectopic Hamartomatous Thymoma: A Review Of The Literature With Report Of New Cases And Proposal Of A New Name: Biphenotypic Branchioma

Cystic Lateral Neck Lesions: Etiologic and Differential Diagnostic Significance in a Series of 133 Patients

Gastrointestinal Malignancy Presenting with a Virchow’s Node in a Patient with Rothmund-Thomson Syndrome

Contact Info

Product

Resources

About