Ethnic differences in glaucoma: prevalence, management, and outcome

Abstract

Our knowledge regarding glaucoma and ethnicity helps us to customize a patient's therapeutic regimen more effectively. Therefore, understanding an individual's heredity and culture is essential to properly identify, treat, and manage individuals at risk and existing patients with glaucoma.

Circadian changes of intraocular pressure and ocular perfusion pressure after timolol or latanoprost in Caucasians with normal-tension glaucoma

“…Although the 24-hour blood pressure (BP) outline of NTG patients has been investigated, documenting nocturnal fluctuations greater than those recorded both in normal and POAG populations [28,33,44], a PubMed-database search highlights the lack of any trial concomitantly verifying the circadian trends of IOP and BP in Caucasian NTG patients. In fact, the existing literature exclusively concerns Japanese NTG clusters [19,22,23,29,43], even if emerging data strongly support the presence of remarkable racial variability with regard to several aspects of open-angle glaucoma care, mainly concerning the differential diagnosis, related to genotypic or phenotypic peculiarities [1,16,37], and the diverse therapeutic responses to anti-glaucoma drugs [21,24,39].…”

Korean normative database for time domain optical coherence tomography to detect localized retinal nerve fiber layer defects (preliminary study)

“…15 There might be differences among different ethnic groups in anatomical structure, prevalence rate, and prevalent type of glaucoma. [16][17][18][19][20] Several researchers have reported variations in RNFL thickness in patients with different ethnicity measured by both OCT and scanning laser polarimetry. [21][22][23][24] For this reason, a normative database of RNFL thickness for each ethnic group is needed.…”

Diclofenac versus fluorometholone after strabismus surgery in children

“…Essentially, this investigation was prompted by the frequent observation of a significant IOP increase in Korean children during the routine use of fluorometholone (over >30 mm Hg at 1 month after strabismus surgery) and by concerns regarding its safe use in children 6. Although there have been reports of an increased risk of open angle, narrow angle and normal tension glaucoma in Asian patients,8 there is no known increased risk of steroid-induced glaucoma in the Asian population 9 10…”