Korean normative database for time domain optical coherence tomography to detect localized retinal nerve fiber layer defects (preliminary study)

Abstract

In detecting localized RNFL defects, the Korean database showed higher sensitivity than the conventional database.

Retinal nerve fiber layer and optic disc measurements by spectral domain OCT: normative values and associations in young adults

“…8 We found that increasing AL and more myopic refraction was associated with thinner average RNFL. This is in agreement with previous Cirrus HD-OCT studies, 6,39 as well as in a study using the Spectralis HRA þ OCT. 26 Studies using the time domain Stratus OCT instrument also reported thinner RNFL with increasing AL or myopic refraction. 7,[9][10][11][12] Using the Topcon spectral domain OCT, Hirasawa et al 27 did not find a relationship with average RNFL thickness or AL in multiple regression analysis.…”

“…Ethnic differences in RNFL thickness were previously reported with older time domain OCT. [6][7][8] The thinner nasal RNFL in East Asians could be explained by the greater prevalence of myopia in this population, which may be associated with a temporal shift in the arcuate nerve fiber bundles. 17 In a study by Knight et al, 16 the European/white sample had an average RNFL of 90.1 mm (SE 0.8) and their Chinese/East Asian sample had average RNFL of 96.4 mm (SE 1.1), compared with our values of 99.5±9.8 mm and 100.1±9.4 mm for these two groups, respectively.…”

Improvement of Diagnostic Performance Regarding Retinal Nerve Fiber Layer Defect Using Shifting of the Normative Database According to Vessel Position

“…Several articles have shown that RNFLs in an Asian population are thicker than in a Caucasian population. [12][13][14] Therefore, before evaluating the vessel contribution to RNFL peaks, an ethnic normative database should have been established using each OCT device. And finding the most contributable factor is imperative to developing an easier approach in our real practice.…”

Normative Values of Retinal Nerve Fibre Layer Thickness and Optic Nerve Head Parameters and Their Association with Visual Function in an African Population

“…Spherical equivalent (SE) of the refractive errors ranged from − 5.25 to + 4.50 dioptres (D), with a mean refractive error of − 0.50 (SD, 1.5). Mean contrast sensitivity was 10.40 triplets (SD, 1.20; range, 5-13 triplets), mean stereoacuity value was 67.65 arc sec (SD, 9.71; range, 15-480 arc sec), and mean intraocular pressure of all participants was 14.79 mmHg (SD, 2.60; range, [10][11][12][13][14][15][16][17][18][19][20]. A 1way analysis of variance followed by post hoc least significant difference for tests for age revealed that, for stereoacuity, contrast sensitivity, IOP, and visual acuity, there was a statistically significant variation (<0.001) between the age groups 19-39 and 60+; then, the age group 40-59 also showed significant variation from age group 60+.…”

“…e OCT, first described by Huang et al [14], gathers information for diagnosing glaucoma and retinal disorders by comparing data it generates with population-derived normative values. Research has however established a strong racial and ocular variation in RNFL thickness and ONH parameters [15][16][17][18][19]. Population-derived normative measures of ONH and RNFL are therefore important to quantify deviations from normal ranges [20][21][22].…”