“…Indeed increased CT levels have been reported in physiological forms of C-cell hyperplasia more often encountered in male subjects over 50 years old (10,11), in renal insufficiency (12), nonmedullary thyroid tumors and autoimmune thyroiditis (13)(14)(15), sepsis (16), hypergastrinemia (17), hypercalcemia (18), pseudohypoparathyroidism type IA (19), omeprazole treatment (20,21), and measurement artifacts, especially induced by heterophilic antibodies (22,23). Also, alcohol (24)(25)(26)(27) and tobacco (28,29) may increase CT but this assertion is mainly based on the acute affect of the drug in animals and humans. Therefore we assessed basal CT levels in a population of patients with chronic alcoholism before and after weaning, in order to investigate the effect of chronic alcoholic intoxication on plasma CT levels.…”