Ethanolic extract of Parkia speciosa Peel: Its effect on alkaline phosphatase and catalase level of wistar rats with “Jelantah” exposed

Widyastuti, Dyah Ayu; Nurdyansyah, Fafa

doi:10.1063/5.0118399

Cited by 3 publications

(5 citation statements)

References 14 publications

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“…The group II dan III were treated with 1 ml jelantah 118 mek/kg then followed with PSPE in a concentration of 100 and 200 mg/kg body weight, respectively. The last group, group IV was treated with only 1 ml jelantah 118 mek/kg for positive control [21]. All treatments were orally administered everyday for four weeks on animal laboratory house.…”

Section: Preparation Of P Speciosa Peel Ethanolic Extract (Pspe)mentioning

confidence: 99%

The effect of stinky bean (Parkia speciosa) peel ethanolic extract to enhance superoxide dismutase (SOD) and reduce malondialdehyde (MDA) level of “jelantah” exposed rats

Nurdyansyah

Widyastuti

Mandasari

2023

IOP Conf. Ser.: Earth Environ. Sci.

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“Jelantah” is cooking palm oil which is used repeatedly. Its daily use leads to enhancement of free radical level in the body. Free radical level should be lowered by a compound named antioxidant, either synthetic or natural antioxidant. This study aims to analyze the effect of P. speciosa peel ethanolic extract (PSPE) to superoxide dismutase (SOD) and malondialdehyde (MDA) level of jelantah exposed Rattus norvegicus (rats). The rats were divided into four groups. There were group I as a negative control (without jelantah and PSPE treatment), group II with 1 ml jelantah 118 mek/kg + 100 mg/kg body weight PSPE treatment, group III with 1 ml jelantah 118 mek/kg + 200 mg/kg body weight PSPE treatment, and group IV is a positive control (with 1 ml jelantah 118 mek/kg). The results showed that range of SOD and MDA level are 20.63-79.06 U/ml and 1.75-9.34 nmol/ml, respectively, with significantly different at α: 0.05. The negative control showed the highest SOD level and lowest MDA level because it was not treated with jelantah. On the other hand, the positive control showed the opposite because it was only treated with jelantah without addition of PSPE. Furthermore, the group III showed higher SOD and lower MDA level than group II. Those indicate that the higher PSPE concentration, the higher SOD level and the lower MDA level. SOD as an antioxidant has contrary level to MDA as free radical. PSPE showed a significant effect to the enhancement of SOD level and the reduction of MDA level in jelantah exposed rats.

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Section: Preparation Of P Speciosa Peel Ethanolic Extract (Pspe)mentioning

confidence: 99%

The effect of stinky bean (Parkia speciosa) peel ethanolic extract to enhance superoxide dismutase (SOD) and reduce malondialdehyde (MDA) level of “jelantah” exposed rats

Nurdyansyah

Widyastuti

Mandasari

2023

IOP Conf. Ser.: Earth Environ. Sci.

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“…The extraction process was based on previous research [1] [3] with maceration method. The empty pods were separated from the seeds then be sliced into smaller pieces.…”

Section: Extraction Of P Speciosa's Empty Podsmentioning

confidence: 99%

“…The ability of EEPE to reduce TCL is predicted as a correlation with its flavonoids content. Flavonoids in the EEPE is well known as antioxidant that can neutralizes oxygen radicals and fatty acids, effectively [1].…”

Section: The Total Cholesterol Level (Tcl)mentioning

confidence: 99%

“…One of Indonesian habits is consuming kind of fried foods especially which are fried with repeated used of palm oil, known as jelantah. These habit is one of dyslipidemia trigger factors in Indonesia [1]. The jelantah is repeatedly heated palm oil until the color has changed which can trigger some harmful compounds in the body due to its high amount of saturated fatty acids.…”

Section: Introductionmentioning

confidence: 99%

“…In this study, the empty pods of P. speciosa, which are usually just thrown away, were assumed as an alternative herbal medicine to treat dyslipidemia condition. It is an abnormal condition of metabolism of lipoprotein, such as abnormality of total cholesterol, LDL (lowdensity lipoprotein), HDL (high-density lipoprotein), and triglyceride status [1]. The P. speciosa empty pods usually ended up in the trash bin because Indonesian only consumes its seeds.…”

Section: Introductionmentioning

confidence: 99%

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The beneficial effect of Parkia speciosa’s empty pods extract on lipid profile of jelantah treated wistar white rats

Nurdyansyah,

Widyastuti

2024

BIO Web Conf.

Self Cite

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Parkia speciosa have many potential properties, as source of antioxidant to combat free radicals, including by dint of jelantah exposure. Its flavonoid content is suspected as an antihiperlipidemia so it can be used as natural treatment to control the lipid profile. This study aims to examine the beneficial effects of the ethanolic extract of P. speciosa’s empty pods (EEPE) on the cholesterol, LDL, HDL, and triglycerides levels in jelantah exposed Wistar rats. The rats were divided into four groups, group I as negative control with no jelantah and EEPE treatment, group II with 1 mL jelantah (118 meq/kg) and 100 mg/kg body weight of EEPE, group III with 1 mL jelantah (118 meq/kg) and 200 mg/kg body weight of EEPE, and group IV as positive control with only jelantah treatment. This study showed that the higher concentration of EEPE able to reduce the cholesterol, LDL, and triglyceride levels also increase the HDL level more than the lower one. However, the treatment of EEPE in group I and II cannot regenerate the lipid profiles in group I as negative control.

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Callus induction of red ginger (Zingiber officinale var. rubrum) with 2,4-D and Kinetin combination to enhance total phenolic and flavonoid content

Widyastuti,

Santosa,

Nuringtyas

et al. 2024

IOP Conf. Ser.: Earth Environ. Sci.

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Plant tissue culture perform as in vitro technique which use any parts of plants under environmental and nutritional control. Tissue culture provides a competitive systems for effective secondary metabolites production, including in red ginger which has many functional properties with high demand in health and pharmaceutical sectors. This study aims to develop an appropriate procedure to cultivate red ginger with in vitro technique to enhance its phenolic and flavonoid content. The rhizome buds were use as explants for callus induction by MS medium with some combination of 2,4-D and kinetin (1:0; 1:1; 1:5; and 5:1). The 70% ethanol, 5,25% sodium hypochlorite, and 10% povidone iodine were used for surface sterilization of bud explants. The result reveals that in 1:0 combination of 2,4-D and Kinetin, the compact callus were initiated on day-16. The other three combinations showed shorter callus forming time in day-14 and they were friable. The 1:1 combination showed the highest percentage (70%) of callus formation compared to other three combinations. In this combination also indicated no contamination occurs. From this in vitro tissue culture, the methanolic extract of callus obtained highest total phenolic content (204,793 µg/mL) than rhizome (130.77 µg/mL). Though, the total flavonoid content of callus extract (0,289 µg/mL) was lower than rhizome extract (6.74 µg/mL). This study showed that the in vitro tissue culture was quite appropriate to enhance total phenolic content in red ginger, although not at the flavonoid content.

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Ethanolic extract of Parkia speciosa Peel: Its effect on alkaline phosphatase and catalase level of wistar rats with “Jelantah” exposed

Cited by 3 publications

References 14 publications

The effect of stinky bean (Parkia speciosa) peel ethanolic extract to enhance superoxide dismutase (SOD) and reduce malondialdehyde (MDA) level of “jelantah” exposed rats

The effect of stinky bean (Parkia speciosa) peel ethanolic extract to enhance superoxide dismutase (SOD) and reduce malondialdehyde (MDA) level of “jelantah” exposed rats

The beneficial effect of Parkia speciosa’s empty pods extract on lipid profile of jelantah treated wistar white rats

Callus induction of red ginger (Zingiber officinale var. rubrum) with 2,4-D and Kinetin combination to enhance total phenolic and flavonoid content

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