The beneficial effect of Parkia speciosa’s empty pods extract on lipid profile of jelantah treated wistar white rats

Abstract

Parkia speciosa have many potential properties, as source of antioxidant to combat free radicals, including by dint of jelantah exposure. Its flavonoid content is suspected as an antihiperlipidemia so it can be used as natural treatment to control the lipid profile. This study aims to examine the beneficial effects of the ethanolic extract of P. speciosa’s empty pods (EEPE) on the cholesterol, LDL, HDL, and triglycerides levels in jelantah exposed Wistar rats. The rats were divided into four groups, group I as negative control with no jelantah and EEPE treatment, group II with 1 mL jelantah (118 meq/kg) and 100 mg/kg body weight of EEPE, group III with 1 mL jelantah (118 meq/kg) and 200 mg/kg body weight of EEPE, and group IV as positive control with only jelantah treatment. This study showed that the higher concentration of EEPE able to reduce the cholesterol, LDL, and triglyceride levels also increase the HDL level more than the lower one. However, the treatment of EEPE in group I and II cannot regenerate the lipid profiles in group I as negative control.