Estudo retrospectivo de lesões em baços de cães esplenectomizados: 179 casos

Bandinelli, Marcele Bettim; Pavarini, Saulo Petinatti; Oliveirã, Eurico C.; Gomes, Danilo Carloto; Cruz, Cláudio Estêvão Farias da; Driemeier, David

doi:10.1590/s0100-736x2011000800011

Cited by 14 publications

(23 citation statements)

References 13 publications

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“…The most frequent tumors diagnosed during this study were hemangiosarcoma 50% (13/26), histiocytic sarcoma 23% (6/26) and lymphoma 11.5% (3/26), with no sex or breed predisposition. Similar results were previously reported with a higher incidence of hemangiosarcoma followed by other sarcomas such as fibrossarcoma, anaplastic sarcoma and leiomyosarcoma (DAY et al, 1995;BANDINELLI et al, 2011). The number, percentage, age, and sex distribution of the cases are presented at Table 1.…”

Section: Resultssupporting

confidence: 84%

“…The most common non-neoplastic changes observed were nodular hyperplasia 24.4% (11/45) followed by infarction 22.3% (10/45) and hematoma 20% (9/45). These disorders were also the main benign alterations observed in canine spleen from previous studies (SPANGLER; CULBERSTON, 1992;DAY et al, 1995;BANDINELLI et al, 2011). The mean age of the dogs was 8.4 years and females (29/45) were overrepresented.…”

Section: Resultssupporting

confidence: 61%

“…Dogs with lymphoma showed spleen involvement in 60% of the cases (JACOBS et al, 2002); however, in this and other studies (DAY et al, 1995;BANDINELLI et al, 2011) a lower incidence was observed in splenectomized dogs. This difference is probably related to the multicentric lymphoma presentation where the treatment of choice is not splenectomy (FOSSUM, 2007;THAMM, 2007).…”

Section: Resultsmentioning

confidence: 46%

“…A greater frequency of splenic non-neoplastic alterations was also reported by Christensen et al (2009). On the other hand, other studies described neoplasms as the most common splenic disorder (DAY et al, 1995;BANDINELLI et al, 2011). Nodular splenic disease was observed in 83.1% (59/71) of the splenectomized dogs; 67.8% (40/59) of these were non-neoplastic and 32.2% (19/59) neoplastic disorders.…”

Section: Resultsmentioning

confidence: 62%

“…This lower incidence of splenic metastasis can be related to an efficient macrophage activity preventing the colonization of tumorous cells (VALLI, 2007;FRY;McGAVIN, 2012). Therefore, metastatic neoplastic disease of the spleen is uncommon (DAY et al, 1995;BANDINELLI et al, 2011), and a previous history of malignant tumor should not be the main criterion for performing a total splenectomy in dogs before a complete systemic investigation is done.…”

Section: Resultsmentioning

confidence: 99%

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Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Silva

Santis

Headley

et al. 2016

SCA

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The spleen of dogs is frequently affected by disorders that vary from local and systemic origin. The difficulty in associating clinical and gross findings contributes for the choice of total splenectomy as the main treatment, leading to an impairment of the immune and hematopoietic functions. The aim of this study was to evaluate the pathological findings in the spleen of splenectomized dogs during 2008 to 2014 at a Veterinary Teaching Hospital. From the 71 cases analyzed, 97,2% (69/71) of the dogs were submitted to total splenectomy and 2,8% (2/71) to partial splenectomy. In 45 (63.4%) of these cases, the histopathological diagnosis was non-neoplastic alterations; only 36.6% (26/71) had a splenic neoplasia. The main non-neoplastic lesions observed were nodular hyperplasia 24.4% (11/45), infarction 22.3% (10/45), and hematoma 20% (9/45). The most frequent tumors were hemangiosarcoma 50% (13/26), histiocytic sarcoma 23% (6/26), and lymphoma 11.5% (3/26). The clinical methods used to diagnose splenic lesions were ultrasonography 88% (63/71), radiography 2.8% (2/71) and exploratory laparotomy 4.2% (3/71). In 4.2% (3/71) of these cases, the splenic changes were observed during therapeutic ovariohysterectomy. Results of the present study showed a prevalence of benign disorders in the spleen of splenectomized dogs associated with a high incidence of total splenectomy performed, indicating a difficulty in recognizing the different lesions that can affect the spleen by the veterinarian medical. Key words: Dogs. Histopathological findings. Splenic disorders. ResumoO baço de cães é frequentemente afetado por alterações locais ou de origem sistêmica. A dificuldade em associar achados clínicos e macroscópicos contribuem para a escolha da esplenectomia total com principal tratamento, levando a um comprometimento das funções imune e hematopoiética. O principal objetivo deste estudo foi avaliar os achados patológicos no baço de cães esplenectomizados durante 2008 a 2014 em um Hospital Escola Veterinário. Dos 71 casos analisados, 97,2% (69/71) dos cães foram submetidos à esplenectomia total e 2,8% (2/71) à esplenectomia parcial. Em 45 (63,4%) casos, o diagnóstico histopatológico foi de alterações não-neoplásicas; somente 36,6% (26/71) tinham neoplasia esplênica. As principais alterações não-neoplásicas observadas foram hiperplasia nodular 24,4% (11/45), infarto 22,3% (10/45) e hematoma 20% (9/45). Os tumores mais frequentes foram

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Section: Resultssupporting

confidence: 84%

Section: Resultssupporting

confidence: 61%

Section: Resultsmentioning

confidence: 46%

Section: Resultsmentioning

confidence: 62%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Splenic lesions observed in 71 splenectomized dogs: a retrospective study

Silva

Santis

Headley

et al. 2016

SCA

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Accuracy of B-mode ultrasound and ARFI elastography in predicting malignancy of canine splenic lesions

Maronezi

Carneiro

Cruz

et al. 2022

Sci Rep

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The objective was to evaluate the accuracy of B-mode ultrasonography and ARFI elastography in detecting malignancy in canine splenic lesions. Thirty-seven spleens with abnormalities (16 benign and 21 malignant) from dogs of different breeds and ages were evaluated. Echogenicity, echotexture, organ length and height were evaluated using B-mode. By ARFI elastography, tissue stiffness was evaluated qualitatively (elastogram) and quantitatively (measuring the shear wave velocity—SWV). Lesions were classified as diffuse, focal or multifocal (cranial, medial or caudal portion) and comparisons of the SWV between the injured and non-injured areas were performed. In the B-mode, no features were associated to malignancy (P > 0.05). In the elastogram, 35 spleens were non-deformable and 2 deformable, having no association with malignancy. The greater SWV was observed in malignant lesions (3.4 ± 0.6 m/s), followed by areas free from alterations (2.1 ± 0.3 m/s) and benign lesions (1.7 ± 0.5 m/s), with difference between groups (P < 0.0001). It was found that a SWV > 2.6 m/s indicates malignancy of canine splenic lesions (sensitivity of 95%, specificity of 100%, PPV of 100%, NPV of 94% and accuracy of 97%), concluding that ARFI elastography is a promising technique for differentiating malignancy in these lesions.

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