Estrogen Dermatitis: Treatment With Progestin-Only Pill

Randall, Katrina L.; Steele, B. Richard

doi:10.1001/archderm.141.6.792

Cited by 13 publications

(6 citation statements)

References 3 publications

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“…Intradermal tests with estrogen are necessary to diagnose estrogen dermatitis. Successful treatment of estrogen dermatitis has been described, including antiestrogen therapy with tamoxifen [43,44], bilateral oophorectomy [46], elimination of oral estrogen therapy [43], using progestin [47] and progesterone therapy [43].…”

Section: Estrogen-induced Urticariamentioning

confidence: 99%

Sex hormones and urticaria

Kasperska−Zając

Brzoza

Rogala

2008

Journal of Dermatological Science

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Section: Estrogen-induced Urticariamentioning

confidence: 99%

Sex hormones and urticaria

Kasperska−Zając

Brzoza

Rogala

2008

Journal of Dermatological Science

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“…Since then 24 more patients have been recognised with this condition [4][5][6][7][8][9][10][11]. It characteristically manifests as cyclical exacerbations of papulovesical lesions, utricaria, eczema or generalised pruritus.…”

Section: Discussionmentioning

confidence: 99%

“…However, its use has been linked to endometrial hyperplasia, endometrial cancer and cervical polyps. There has been a single case report where the condition was successfully treated with the continuous progesterone contraception pill [10]. Moreover GnRH analogues have been used in the past with good response [11].…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic bilateral salpingo-oophorectomy as treatment for oestrogen dermatitis: a case report

Manias

Panayotidis

2008

Gynecol Surg

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“…40 Successful treatment has been demonstrated with suppression of estrogen with estrogen modulators, such as leuprolide acetate 41 or tamoxifen. 38,39 Other effective approaches include progestin-only contraceptive 42 or oophorectomy. 37 Patients who are symptomatic because of exogenous estrogen exposure have been able to mitigate symptoms by stopping estrogen therapy.…”

Section: Estrogen Hypersensitivitymentioning

confidence: 99%

Cyclical hypersensitivity, anaphylaxis, and related hormonal reaction

Lavery

Bernstein

2019

Annals of Allergy, Asthma & Immunology

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Although endogenous or exogenous exposure to progesterone or estrogen that induce a spectrum of hypersensitivity reactions and/or other skin eruptions are believed to be uncommon, their prevalence is currently unknown. Clinical manifestations are heterogeneous but typically involve cyclical manifestation of a spectrum of dermatitis conditions and/or systemic symptoms. Diagnosis is made primarily by history in conjunction with in vitro assays to measure specific IgE and provocation challenge testing when appropriate; judicious use of skin testing is recommended because of their irritant-causing effects. Pathomechanisms are incompletely understood but likely involve IgE-mediated immediate-type hypersensitivity. Treatment is aimed at symptomatic control with nonsedating histamine 1 antihistamines, short-term use of systemic glucocorticoids, progesterone desensitization, and/or suppression of ovulation by a pharmacologic or, as a last resort, surgical approach. Instructions Credit can now be obtained, free for a limited time, by reading the review article and completing all activity components. Please note the instructions listed below: Review the target audience, learning objectives and all disclosures. Complete the pre-test. Read the article and reflect on all content as to how it may be applicable to your practice. Complete the post-test/evaluation and claim credit earned. At this time, physicians will have earned up to 1.0 AMA PRA Category 1 Credit TM. Minimum passing score on the post-test is 70%. Overall Purpose Participants will be able to demonstrate increased knowledge of the clinical treatment of allergy/asthma/immunology and how new information can be applied to their own practices.

show abstract

Estrogen Dermatitis: Treatment With Progestin-Only Pill

Cited by 13 publications

References 3 publications

Sex hormones and urticaria

Sex hormones and urticaria

Laparoscopic bilateral salpingo-oophorectomy as treatment for oestrogen dermatitis: a case report

Cyclical hypersensitivity, anaphylaxis, and related hormonal reaction

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