Estimating peak oxygen uptake in adolescents with cystic fibrosis

Abstract

In the absence of direct VO2 peak assessment it is possible to estimate VO2 peak in adolescents with CF using only a cycle ergometer. Furthermore, the regression model showed to be able to discriminate patients in different prognosis clusters based on exercise capacity.

Challenges in Implementing Routine Cardiopulmonary Exercise Testing in Cystic Fibrosis Clinical Practice: a Single-Centre Review

“…in the post-transplant setting) although CPET may only be deemed useful for those predicted long-term survival and accompanying treatment plans. Furthermore, patients who presented with microbiological contraindications to performing a CPET with full on-line gas analysis (n = 13) were still able to undertake CPET using a protocol from Werkman et al [11], whereby peak power achieved can act as a proxy for aerobic fitness, and in adolescents with CF, predict VȮ 2peak .…”

2014 year in review: Cystic fibrosis

“…Comparison of children with mild CF to controls did not reveal differences in mechanical ventilatory constraints, defined by expiratory flow limitation and dynamic hyperinflation, during incremental exercise . A validated equation to estimate VO 2 peak using work rate and gender demonstrated reasonable positive and negative predictive values . Another study suggested that heart rate recovery may reflect VO 2 peak during exertion and recovery from the 3‐min step test, a submaximal exercise test, in children 8–19 years of age .…”

Exercise Testing in Children with Cystic Fibrosis

“…At the end of the study, it is concluded that if the VO 2peak can not be measured directly, the estimated value of VO 2peak can be obtained only by bicycle ergometer. 23 Saynor et al measured aerobic fitness (VO 2max ) in 14 children with cystic fibrosis aged 7-18, using the ramp protocol in maximal CPET. In the study, 14 children completed the exhausting ramp test to determine VO 2max .…”