Challenges in Implementing Routine Cardiopulmonary Exercise Testing in Cystic Fibrosis Clinical Practice: a Single-Centre Review

Tomlinson, Owen W.; Trott, J.; Williams, Craig A.; Withers, Nicholas; Oades, Patrick

doi:10.1007/s42399-020-00239-7

Cited by 5 publications

(6 citation statements)

References 13 publications

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“…The first of these emails was received in April 2018, 3 months after the author had submitted an abstract (and contact details) to an international conference. Moreover, a notable increase in the volume of emails was noted early in 2020, shortly after the publication of two articles (Tomlinson et al, 2020; Tomlinson & Vlachopoulos, 2020) whereby the author's email was provided as correspondence.…”

Section: Resultsmentioning

confidence: 99%

Analysis of predatory emails in early career academia and attempts at prevention

Tomlinson

2022

Learned Publishing

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Predatory publishersthose who do not adhere to rigorous standards of academic practice such as peer revieware increasingly infiltrating biomedical databases, to the detriment of the wider scientific community. These publishers frequently send unsolicited 'spam' emails to generate submission to their journals, with early career researchers (ECR) particularly susceptible to these practices because of pressures such as securing employment and promotion. This analysis sought to record and characterise the emails received over the course of a PhD and postdoctoral position (~8 years), as well as attempts to unsubscribe from such emails, using a progressive and step-wise manner. A total of 1280 emails identified as academic spam were received (990 journal invitations, 220 conference invitations, 70 'other'). The first email was received three months after registration for an international conference. Attempts at unsubscribing were somewhat effective, whereby implications of reporting to respective authorities resulted in a 43% decrease in emails, although did not eliminate them completely, and therefore alternative approaches to eliminating academic spam may be needed. Ongoing education about predatory publishers, as well as action by key academic stakeholders, should look to reduce the impact these predatory publishers have upon the wider literature base.

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Section: Resultsmentioning

confidence: 99%

Analysis of predatory emails in early career academia and attempts at prevention

Tomlinson

2022

Learned Publishing

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“…Whilst every endeavour is made to perform annual exercise tests on each patient, this may not always happen. In addition, given that pulmonary function is a predictor of whether patients will undergo annualised CPET ( Tomlinson et al, 2020 ), it is feasible that disease progression has directly affected follow-up results being obtained in this cohort.…”

Section: Discussionmentioning

confidence: 99%

The Effect of Dysglycaemia on Changes in Pulmonary and Aerobic Function in Cystic Fibrosis

et al. 2022

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Cross-sectional studies have reported lower pulmonary and aerobic function during exercise in people with cystic fibrosis-related diabetes (CFRD) compared to non-CFRD counterparts. However, this association has yet to be longitudinally investigated. Therefore, this study examines these differences over time between people with cystic fibrosis (CF) of differing glycaemic status. Annual review data, including cardiopulmonary exercise tests and pulmonary function tests, were retrospectively analysed at baseline (T0, n = 82) and at a one-year follow-up (T1, n = 54). Data was analysed in three groups: normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and CFRD. Further analyses were undertaken, with a dichotomous split of NGT and a combined IGT/CFRD group. At baseline, a significant reduction in the majority of variables, including forced expiratory volume in one second (FEV1) and maximal oxygen uptake (VO2max), was observed in the CFRD (n = 19) group compared to NGT (n = 58). At follow-up, no significant differences were observed, and no interaction effect between CFRD status and time was identified. FEV1 and VO2max presented with varying directions and magnitudes of change within patients. In summary, patients with CFRD have a reduced aerobic and pulmonary function compared to non-CFRD counterparts, although such changes disappeared at follow up. Varying responses for FEV1 and VO2max highlight the need to consider both variables as independent markers of function in CF.

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“…Although the use of CPET is increasing in some countries [ 8 , 9 ], CPET is not the only test of aerobic fitness and remains unavailable in many clinics for reasons of testing time, space, cost, expertise or clinician availability [ 10 – 14 ], as well as patient preference and certain pathogens prohibiting analysis of ventilatory parameters. Indeed, a recent UK-based survey [ 8 ] demonstrated that whilst exercise testing has increased from 54% of centres using some form of exercise testing in 2010 [ 10 ] to 94% in 2021, only 48% of these currently use CPET, despite considerable investment in the guidance for this ( e.g .…”

Section: Introductionmentioning

confidence: 99%

Guidance and standard operating procedures for functional exercise testing in cystic fibrosis

et al. 2023

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Regular exercise testing is recommended for all people with cystic fibrosis (PwCF). A range of validated tests, which integrate both strength and aerobic function, are available and increasingly being used. Together, these tests offer the ability for comprehensive exercise evaluation. Extensive research and expert consensus over recent years has enabled the adaptation and standardisation of a range of exercise tests to aid the understanding of the pathophysiology related to exercise limitation in PwCF and has led to the development of novel exercise tests which may be applied to PwCF. This article provides expert, opinion-based clinical practice guidance, along with test instructions, for a selection of commonly used valid tests which have documented clinimetric properties for PwCF. Importantly, this document also highlights previously used tests that are no longer suggested for PwCF and areas where research is mandated. This collaboration, on behalf of the European Cystic Fibrosis Society Exercise Working Group, represents expert consensus by a multidisciplinary panel of physiotherapists, exercise scientists and clinicians and aims to improve global standardisation of functional exercise testing of PwCF. In short, the standardised use of a small selection of tests performed to a high standard is advocated.

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Challenges in Implementing Routine Cardiopulmonary Exercise Testing in Cystic Fibrosis Clinical Practice: a Single-Centre Review

Cited by 5 publications

References 13 publications

Analysis of predatory emails in early career academia and attempts at prevention

Analysis of predatory emails in early career academia and attempts at prevention

The Effect of Dysglycaemia on Changes in Pulmonary and Aerobic Function in Cystic Fibrosis

Guidance and standard operating procedures for functional exercise testing in cystic fibrosis

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