Establishing the prevalence of hypertension. Influence of sampling criteria

Petter, Juliano Gueno; Accordi, M; Zen, Vanessa Ligocki; Pizzol-Jr, Antônio D.; Moreira, Leila Beltrami; Fuchs, Flávio Danni

doi:10.1590/s0066-782x2001000600002

Cited by 19 publications

(21 citation statements)

References 8 publications

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“…Nevertheless, only 27% of the hypertensive patients achieved blood pressure control, much lower than the desirable rate. This is similar to findings from other studies done in Brazil 6,8 and developed countries, 9,10 and it demonstrates the difficulty in achieving such a goal, which requires a search for new strategies and a change of approach to arterial hypertension. The higher the number of risk factors was, the poorer the hypertension control (Figure 5), probably because of the metabolic conditions associated.…”

Section: Discussionsupporting

confidence: 89%

“…1,2,3 Arterial hypertension is the most frequent treatable cardiovascular risk factor for death, 2,3,4 with prevalence ranging from 10 to 44% in different studies and countries. [4][5][6][7][8][9][10] Without symptoms in its initial stage, hypertension is generally diagnosed only when complications appear, thus causing significant losses in quality of life and increasing mortality rates. The costs for society are high, because this condition requires tertiary care and affects an economically active part of the population.…”

Section: Introductionmentioning

confidence: 99%

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Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

et al. 2004

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CONTEXT: Hypertension is one of the most important cardiovascular risk factors but its control is still a challenge for physicians all around the world. For blood pressure control to be improved, it is important to guarantee the quality of attendance provided for hypertensive patients, especially in teaching hospitals, where future physicians are being trained. OBJECTIVE: To characterize the profile of hypertensive patients attending the internal medicine outpatient clinic of a university hospital in Rio de Janeiro,describing their cardiovascular risk and identifying flaws in the treatment provided for severely hypertensive patients, in order to implement an arterial hypertension management program. TYPE OF STUDY: A descriptive cross-sectional population-based study. SETTING: Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro. METHODS: The study was carried out over a period of four months, involving all the hypertensive patients under treatment in the outpatient unit. The attending physician obtained information relating to demographic features, cardiovascular risk factors, target organ damage, blood pressure levels, therapeutic regimens and compliance with treatment. Means and the respective standard deviations and proportions were used to describe the distribution of patient data. RESULTS: Of the total number of patients seen, 24.2% (1,699 patients) were hypertensive. Women accounted for 65.0% of the patients. The mean age was 63.9 years. Dyslipidemia (49.2%) and diabetes (29.8%) were the most frequently reported risk factors and heart disease was the most prevalent end-organ damage. Seventy percent of the patients were classified as high cardiovascular risk. In spite of the high intensity treatment provided for the most severe patients (19.4% on a regimen of 3 or more antihypertensive drugs), the rate of blood pressure control was low (27%). CONCLUSIONS: The patients with arterial hypertension under treatment at the university hospital had a profile of high cardiovascular risk and poor blood pressure control. Greater effort for improving hypertension control is needed, since this is the only way to reduce the morbidity and mortality rates of cardiovascular diseases.

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

et al. 2004

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“…Other studies also detected an association between hypertension and family history 3,5,20,21 . The positive association between hypertension and obesity was also observed in other studies 3,19,20,22 .…”

Section: Discussionmentioning

confidence: 85%

“…Population-based studies carried out in Brazil have shown that hypertension is a common disease, the prevalence of which is about 20% [2][3][4][5] . Today, cardiovascular diseases constitute the primary cause of death, representing roughly one-third of overall adult mortality in Brazil.…”

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confidence: 99%

Prevalência de hipertensão arterial em adultos e fatores associados: um estudo de base populacional urbana em Pelotas, Rio Grande do Sul, Brasil

Costa¹,

Barcellos²,

Sclowitz³

et al. 2007

Arq. Bras. Cardiol.

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101

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Objective: To determine hypertension prevalence and its associated risk factors. Methods:A cross-sectional, population-based study of people ages 20 to 69 living in the urban area of Pelotas, Rio Grande Hg (average of two readings) or current use of antihypertensive drugs.Results: Among the 1,968 subjects enrolled in the study, hypertension prevalence was 23.6% (95% CI 21.6 to 25.3). A Poisson regression model was used to control confounding factors effects. The following variables remained statistically significant in the final model: family income, age, skin color, gender, family history of hypertension, extra salt intake, and body mass index. Conclusion:Compared with a similar study undertaken in 1992, hypertension prevalence increased, particularly in the younger groups.

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“…With the increasing life expectancy of the general population, there is an increased prevalence of many chronic diseases, such as hypertension (Fuchs et al, 2001). Hypertension is characterized by maintenance of sustained high blood pressure levels (above 140/80 mmHg) (Chobanian et al, 2003;WHO, 2003), and it contributes significantly to serious complications such as stroke, myocardial infarction, congestive heart failure, and chronic renal failure (WHO, 1999;Chobanian et al, 2003;WHO, 2003;Kaplan, Opie, 2006;Thayer, Lane, 2007).…”

Section: Introductionmentioning

confidence: 99%

Hypotensive effect and endothelium-dependent vascular action of leaves of Alpinia purpurata (Vieill) K. Schum

Silva

Lima

Caliman

et al. 2014

Braz. J. Pharm. Sci.

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The aims of this study were to evaluate the chemical profile, vascular reactivity, and acute hypotensive effect (AHE) of the ethanolic extract of leaves of Alpinia purpurata (Vieill) K. Schum (EEAP). Its chemical profile was evaluated using HPLC-UV, ICP-OES, and colorimetric quantification of total flavonoids and polyphenols. The vascular reactivity of the extract was determined using the mesenteric bed isolated from WKY. AHE dose-response curves were obtained for both EEAP and inorganic material isolated from AP (IAP) in WKY and SHR animals. Cytotoxic and mutagenic safety levels were determined by the micronucleus test. Rutin-like flavonoids were quantified in the EEAP (1.8 ± 0.03%), and the total flavonoid and polyphenol ratios were 4.1 ± 1.8% and 5.1 ± 0.3%, respectively. We observed that the vasodilation action of EEAP was partially mediated by nitric oxide ( ). The EEAP and IAP showed an AHE in WKY and SHR animals. EEAP did not have cytotoxic effects or cause chromosomic alterations. The AHE shown by EEAP could result from its endothelium-dependent vascular action. Rutin-like flavonoids, among other polyphenols, could contribute to these biological activities, and the calcium present in EEAP could act in a synergistic way.Uniterms: Alpinia. Alpinia purpurata/phytochemistry. Alpinia purpurata/ethanolic extract/vascular reactivity. Alpinia purpurata/ethanolic extract/acute hypotensive effect. Flavonoids/quantification. Polyphenols/quantification.Os objetivos deste estudo foram avaliar o perfil químico de folhas de Alpinia purpurata K. Schum (AP), assim como a reatividade vascular e o efeito hipotensor agudo (EHA) do extrato etanólico de folhas de AP (EEAP). Avliou-se o perfil químico utilizando-se HPLC-UV, ICP-OES e quantificação colorimétrica de flavonoides e polifenóis totais. A reatividade vascular foi determinada utilizando leito mesentérico isolado de ratos WKY. Curvas dose-resposta do EEAP e do material inorgânico da AP (IAP) foram realizadas em animais SHR e WKY. Determinaram-se a segurança citotóxica e mutagênica pelo teste de micronúcleos. Flavonoides tipo rutina foram quantificados no EEAP (1,8±0,03%) e flavonoide total e polifenóis foram de 4,1±1,8% e 5,1±0,3%, respectivamente. Observou-se ação vasodilatadora do EEAP, mediada parcialmente pelo óxido nítrico (

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Establishing the prevalence of hypertension. Influence of sampling criteria

Abstract: Prevalence rates of hypertension differed a lot in the campaign sample and in the representative population sample, showing that the sampling criterion may influence assessment of risk factors and bias the association between risk factors and health aggravations.

Cited by 19 publications

References 8 publications

Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

Prevalência de hipertensão arterial em adultos e fatores associados: um estudo de base populacional urbana em Pelotas, Rio Grande do Sul, Brasil

Hypotensive effect and endothelium-dependent vascular action of leaves of Alpinia purpurata (Vieill) K. Schum

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