Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

Muxfeldt, Elizabeth S.; Nogueira, Armando da Rocha; Salles, Gil F.; Bloch, Katia Vergetti

doi:10.1590/s1516-31802004000300003

Cited by 28 publications

(21 citation statements)

References 11 publications

(18 reference statements)

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“…According WHO (2003), the hypertension afflicts approximately 600 million people around the world, including the majority of elderly, and imposes enormous burdens through associated cardiovascular diseases. In Brazil, cardiovascular diseases remain the leading cause of death reaching 32% of all causes of mortality (Muxfeldt et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

“…These preventable negative patient outcomes and their associated costs have caught the attention of patients, healthcare professionals, and governmental agencies (Kohn et al, 1999) In Brazil, most elderly patients with hypertension are using prescribed drugs by the Public Health Care System (SUS) to control the disease. Despite such therapy, most of patients have inadequate blood pressure (BP) control, with increased risk of associated cardiovascular morbidity and mortality (Zaitune et al, 2006;Muxfeldt et al, 2004). This uncontrolled hypertension is commonly associated with non-adherence to drug therapy and/or lack of access to health care (Chobanian, 2001).…”

Section: Introductionmentioning

confidence: 99%

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Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Júnior

Marcellini

Pelá

2008

Rev. Bras. Cienc. Farm.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Júnior

Marcellini

Pelá

2008

Rev. Bras. Cienc. Farm.

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“…This is the first time that prevalence of RH was assessed in such a large cohort of patients. Previous reports were carried out in single referral units 3,8,17,18 or indirectly estimated from randomized clinical trials. 19 Mean values of RH prevalence in such situations have been estimated at Ϸ20%, 1 which is a somewhat higher with respect to the figure presented here.…”

mentioning

confidence: 99%

Clinical Features of 8295 Patients With Resistant Hypertension Classified on the Basis of Ambulatory Blood Pressure Monitoring

Sierra

Segura²,

Banegas³

et al. 2011

Hypertension

642

303

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Abstract-We aimed to estimate the prevalence of resistant hypertension through both office and ambulatory blood pressure monitoring in a large cohort of treated hypertensive patients from the Spanish Ambulatory Blood Pressure Monitoring Registry. In addition, we also compared clinical features of patients with true or white-coat-resistant hypertension. In December 2009, we identified 68 045 treated patients with complete information for this analysis. Among them, 8295 (12.2% of the database) had resistant hypertension (office blood pressure Ն140 and/or 90 mm Hg while being treated with Ն3 antihypertensive drugs, 1 of them being a diuretic). After ambulatory blood pressure monitoring, 62.5% of patients were classified as true resistant hypertensives, the remaining 37.5% having white-coat resistance. The former group was younger, more frequently men, with a longer duration of hypertension and a worse cardiovascular risk profile. The group included larger proportions of smokers, diabetics, target organ damage (including left ventricular hypertrophy, impaired renal function, and microalbuminuria), and documented cardiovascular disease. Moreover, true resistant hypertensives exhibited in a greater proportion a riser pattern (22% versus 18%; PϽ0.001). In conclusion, this study first reports the prevalence of resistant hypertension in a large cohort of patients in usual daily practice. Resistant hypertension is present in 12% of the treated hypertensive population, but among them more than one third have normal ambulatory blood pressure. A worse risk profile is associated with true resistant hypertension, but this association is weak, thus making it necessary to assess ambulatory blood pressure monitoring for a correct diagnosis and management. (Hypertension. 2011;57:898-902.) • Online Data Supplement Key Words: resistant hypertension Ⅲ ambulatory blood pressure monitoring Ⅲ circadian pattern Ⅲ cardiovascular risk R esistant hypertension (RH) is defined as office blood pressure (BP) that remains above goal despite the concurrent use of 3 antihypertensive agents, at full doses, one of them being a diuretic. Although the prevalence of RH largely depends on the setting explored, this condition is of clinical importance, because it is associated with an impaired prognosis. 1 The definition of RH is based on office measurements. However, the use of ambulatory BP monitoring (ABPM) has allowed for the recognition of the white-coat effect as being responsible for a proportion of resistant hypertensive patients. It is estimated that approximately one third of patients with suspected RH indeed have white-coat or isolated office RH, showing normal daytime or 24-hour ABPM values. [2][3][4] Elevated ABPM values in patients with RH are associated with a higher prevalence of target organ damage 4,5 and increased incidence of future cardiovascular events. 6 -8 However, these data come from relatively small populations attended in single referral units, whereas there is lack of data coming from large hypertensive populations representi...

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“…The characteristics of this cohort as well as the baseline procedures and the diagnostic definitions have already been detailed elsewhere [7]. Demographic and anthropometric characteristics as well as cardiovascular risk factors and target-organ damage information were recorded.…”

Section: Overview and Study Populationmentioning

confidence: 99%

Office blood pressure and 24-hour ambulatory blood pressure measurements: high proportion of disagreement in resistant hypertension

Rodrigues

Bloch

Nogueira

2009

Journal of Clinical Epidemiology

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Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro

Cited by 28 publications

References 11 publications

Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Effect of pharmaceutical care intervention on blood pressure of elderly outpatients with hypertension

Clinical Features of 8295 Patients With Resistant Hypertension Classified on the Basis of Ambulatory Blood Pressure Monitoring

Office blood pressure and 24-hour ambulatory blood pressure measurements: high proportion of disagreement in resistant hypertension

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