Essential oil composition, phenolic compound, and antioxidant potential of <i>Inulaviscosa </i>as affected by extraction process

Eljazi, Jazia Sriti; Selmi, Sawssen; Zarroug, Youkabed; Wesleti, Ibtissem; Aouini, Bouthaina; Jallouli, Sélim; Limam, Férid

doi:10.1080/10942912.2018.1517782

Cited by 16 publications

(9 citation statements)

References 38 publications

(49 reference statements)

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“…This disadvantage restricts its application for thermolabile compound extraction. Sriti Eljazi et al () described that the extraction yields of flavonoids including luteolin with HDE are higher as compared with the MAE and ME.…”

Section: Extraction Techniquesmentioning

confidence: 99%

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

et al. 2019

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Luteolin is a 3′, 4′, 5, 7 tetra hydroxyl flavonoid that exits in many plants, fruits, and vegetable. Many methods of extraction, isolation, and purification are being used, and therapeutic properties are being under discussion due to its valuable role in nutrition and human health. In this review, we have summarized conventional and novel extraction techniques from most recent research on luteolin, its derivatives, and its biological activities. Maceration, soxhlet, reflux, hydrodistillation, ultrasound‐assisted extraction, microwave‐assisted extraction, ultrasound microwave‐assisted extraction, enzyme‐assisted extraction, supercritical fluid extraction, and high‐speed counter‐current chromatography extraction techniques are being used for isolation and purification of these phytochemicals. The anti‐inflammatory, anti‐cancer, antioxidant, antiviral, heart protective, neurological impairments protection, anti‐aging, and whiting properties have been discussed in this review. The literature suggests luteolin and its derivative has many promising health benefits and its therapeutic activity is strongly associated with isolating and purifying solvents and extraction techniques. Practical applications This review aims to highlight the sources, novel extraction techniques, and pharmaceutical properties of luteolin. This review provides enough knowledge about how to get maximum extraction yield of luteolin using the novel extraction techniques. Because its therapeutic activity is strongly associated with isolating and purifying solvents and techniques.

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Section: Extraction Techniquesmentioning

confidence: 99%

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

et al. 2019

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“…The lipophilic (essential oil) and hydrofracture (hydrosol) collected from the inner tube of the Clevenger apparatus differ in chemical composition and biological activity due to the difference in solubility of the volatile compounds. In addition to water distillation, some authors have performed steam distillation, solvent extraction, and extraction by ultrasonic distillation from plant material of the genus Inula [8][9][10]. They obtained significant differences in the yield and composition of the essential oil [8].…”

Section: Gas Chromatography and Mass Spectrometry (Gc-ms) Analysis Of The Free Volatile Compounds From Essential Oil And Hydrosolmentioning

confidence: 99%

“…As an aromatic species with intense odor, this plant has been the subject of phytochemical profiling of volatile components performed by steam distillation, solvent extraction, and extraction by ultrasonic distillation [8][9][10]. The composition of the essential oil of D. viscosa is described in a large number of scientific papers and the main components of the essential oil obtained from different countries and regions are listed in the work of Zouaghi et al [8].…”

Section: Introductionmentioning

confidence: 99%

Not Only a Weed Plant—Biological Activities of Essential Oil and Hydrosol of Dittrichia viscosa (L.) Greuter

Vuko

Dunkić

Maravić

et al. 2021

Plants

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With the increasing interest in obtaining biologically active compounds from natural sources, Dittrichia viscosa (L.) Greuter (Asteraceae) came into our focus as a readily available and aromatic wild shrub widely distributed in the Mediterranean region. This work provides a phytochemical profile of D. viscosa in terms of parallel chemical composition in the lipophilic fraction (essential oil) and the water fraction (hydrosol). GC-MS analysis identified 1,8-cineole, caryophyllene oxide, α-terpenyl acetate, and α-muurolol as the major components of the essential oil, while in the hydrosol p-menth-1-en-9-ol, 1,8-cineole, linalool, cis-sabinene hydrate, and α-muurolol were the major volatile components. 3,4-Dihydroxybenzoic acid was found to be the predominant compound in the hydrosol composition by HPLC analysis. The antimicrobial potential of both extracts was evaluated against thirteen opportunistic pathogens associated with common skin and wound infections and emerging food spoilage microorganisms. The antimicrobial activity of the essential oil suggests that the volatiles of D. viscosa could be used as novel antimicrobial agents. The antiproliferative results of D. viscosa volatiles are also new findings, which showed promising activity against three cancer cell lines: HeLa (cervical cancer cell line), HCT116 (human colon cancer cell line), and U2OS (human osteosarcoma cell line). The decrease in GSH level observed in hydrosol-treated HeLa cells suggests oxidative stress as a possible mechanism of the antiproliferative effect of hydrosol on tumor cells. The presented results are also the first report of significant antiphytoviral activity of hydrosol against tobacco mosaic virus (TMV) infection. Based on the results, D. viscosa might have the potential to be used in crop protection, as a natural disinfectant and natural anticancer agent.

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“…They concluded that the reflux technique using methanol as a solvent is better than the other extraction techniques [234]. Hydrodistillation was also used for flavonoids extraction including luteolin [235]. Besides, microwave-assisted extraction technique was employed in extraction of luteolin, and it was reported that this method is more efficient and produced higher extraction yield compared to maceration and heat reflux extraction methods [233].…”

Section: Luteolinmentioning

confidence: 99%

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

et al. 2020

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Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a priority. In this review, we describe the main plant-derived natural products used as anticancer agents. Natural sources, extraction methods, anticancer mechanisms, clinical studies, and pharmaceutical formulation are discussed in this review. Studies covered by this review should provide a solid foundation for researchers and physicians to enhance basic and clinical research on developing alternative anticancer therapies.

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Essential oil composition, phenolic compound, and antioxidant potential of Inulaviscosa as affected by extraction process

Cited by 16 publications

References 38 publications

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives

Not Only a Weed Plant—Biological Activities of Essential Oil and Hydrosol of Dittrichia viscosa (L.) Greuter

Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

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