ESR investigation of gamma irradiated sulbactam sodium

Yürüş, S.; Özbey, Turan; Korkmaz, Mustafa

doi:10.1016/j.jpba.2004.03.012

Cited by 11 publications

(6 citation statements)

References 19 publications

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“…Mathematical equations that show the best fit of the samples and correlation coefficient (R 2 ) are given in Table 2. This comment agree with results obtained for various kind of drugs studied before [16][17]. In these functions, I and D are used for EPR signal intensity and treated irradiation dose in kGy, respectively and other parameters are constants to be determined.…”

Section: Resultssupporting

confidence: 88%

Işınlama Dozunun ve Depolama Süresinin Gama ile Işınlanmış Sülfapridinin Sinyal Şiddeti Üzerine Etkisi

Sütçü

2016

El-Cezeri Fen Ve Mühendislik Dergisi

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Section: Resultssupporting

confidence: 88%

Işınlama Dozunun ve Depolama Süresinin Gama ile Işınlanmış Sülfapridinin Sinyal Şiddeti Üzerine Etkisi

Sütçü

2016

El-Cezeri Fen Ve Mühendislik Dergisi

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“…Mathematical equations that show the best fit of the samples and correlation coefficient (R 2 ) are given in Table 2. This comment agrees with results obtained for various kind of drugs studied before [26,27]. In these functions, I and D are used for EPR signal intensity and treated irradiation dose in kGy, respectively and other parameters are constants to be determined.…”

Section: Dose-response Curvessupporting

confidence: 87%

Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders

Osmanoğlu

Sütçü

2018

Cumhuriyet Science Journal

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In this study, gamma rays were applied to the sulfadimethoxine, pyrazinamide, and chloramphenicol in the dose range of 1-15 kilogray, in order to detect radiosensitivity of paramagnetic species, which are formed after irradiation by electron paramagnetic resonance spectroscopy. Firstly, the intensities of electron paramagnetic resonance signals of the samples as a function of the microwave power were investigated at room temperature. While no signal was obtained from the unirradiated samples, the irradiated samples exhibited significant spectra. Additionally, the time dependency of the samples was analyzed to study the stability of the radicals.

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“…However, there is no single ideal method for this selection. Linear, exponential and polynomial functions are frequently used for this purpose [9,[18][19][20]. Several mathematical functions were tried to describe evolution of the central EPR signal with absorbed radiation dose.…”

Section: Resultsmentioning

confidence: 99%

Study of dose-response and radical decay curves of gamma irradiated norfloxacin using EPR spectroscopy

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Osmanoğlu²

2017

AIP Conference Proceedings

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In this study, Electron Paramagnetic Resonance (EPR) spectra of unirradiated and γ-irradiated at doses of 1, 5, 10, 12 and 15 kGy norfloxacin (NOF) were investigated. Before irradiation no EPR signal were observed. After irradiation a weak singlet signal at g = 2.0039 were obtained at room temperature. In order to describe the variation of EPR signal intensity with absorbed radiation dose, several mathematical equations were tried. Increasing irradiation dose up to 15 kGy has increased the signal intensity of the central signal however, no significant changes were observed in g spectroscopic splitting factor. The stability of signal intensity of irradiated NOF was studied over a storage period of 200 days. According to analyses conducted, EPR spectroscopy can be used to distinguish irradiated and unirradiated samples from each other.

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ESR investigation of gamma irradiated sulbactam sodium

Cited by 11 publications

References 19 publications

Işınlama Dozunun ve Depolama Süresinin Gama ile Işınlanmış Sülfapridinin Sinyal Şiddeti Üzerine Etkisi

Işınlama Dozunun ve Depolama Süresinin Gama ile Işınlanmış Sülfapridinin Sinyal Şiddeti Üzerine Etkisi

Electron Paramagnetic Resonance Investigation of Radiation Effect on Certain Types of Drug Powders

Study of dose-response and radical decay curves of gamma irradiated norfloxacin using EPR spectroscopy

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