Erythrocyte Glyoxalase I and Esterase D Polymorphisms in Four French Populations

Abstract

The genetic polymorphism of two new erythrocyte markers GLO I (EC 4.4.1.5) and esterase D (EC 3.1.1.1) has been investigated in four French populations: Basques and Toulouse groups (southwest area), Lille and Strasbourg (northern and eastern part of the territory). The distribution of GLO I and EsD alleles within these communities has shown some significant differences. Basques samples are characterized by the highest frequency of EsD¹ gene (0.911) and the lower rate of GLO¹(0.364). The observed data are compared with other results previously reported in France and in Western European populations.

New Contribution to the Genetics of the Basques: Heterogeneity in the Esterase D Subtype Distribution

“…The values found in this study for allele ESD*I in the Basque population of Vizcaya and Guipúzcoa (0.933 and 0.938, respectively) are similar to that found in the other Basque series [1,[6][7][8][9]. However, the Basque popula tion from Alava displays the lowest frequency of allele ESD*1 of any Basque series thus far analyzed.…”

Esterase D Polymorphism in Galicia (North-West of Spain)

“…zones with ester ase activity appeared as bright fluorescent bands against a dark background under UV light at 360 nm. [Vergnes et al, 1980). The Galician population presents a gene frequency (EsD-= 0.1087) very similar to that of studies of other European populations.…”

Glutamate Pyruvate Transaminase, Esterase D, Glyoxalase 1, and Phosphoglucomutase 1 Polymorphisms in Porto District (Portugal)

“…The GLO' frequency in European popu lations studied up to now is found to range between 0.43 and 0.47, with the exceptions of small samples studied or cited by Vergnes et al [1980]. So our findings (GLO' = 0.43) fit well in this distribution, but in its lower limit.…”

“…Esterase D ESD2 has a higher frequency than in any other European population, Lapland ex- cepted [ Pa pi ha and Nahar, 1977;Vergnes et al, 1980].…”