Eryngium creticum – ethnopharmacology, phytochemistry and pharmacological activity. A review

Kikowska, Małgorzata; Dworacka, Marzena; Kędziora, Izabela; Thiem, Barbara

doi:10.1016/j.bjp.2016.01.008

Cited by 21 publications

(31 citation statements)

References 27 publications

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“…Moreover, most of the bitter compounds used in this study are common in plants. For example, beta-glucopyranosides and camphor can be found in two plant species ( Ranunculus asiaticus and Eryngium creticum ) growing in both soils ( Toki et al 1996 ; Lövy et al 2015 ; Kikowska et al 2016 ); the latter is the most frequent plant in the chalk soil at the studied microsite ( Lövy et al 2015 ). In other words, these bitter compounds or other compounds with similar chemical structures occur in the daily food of mole rats living in the two soils.…”

Section: Discussionmentioning

confidence: 99%

Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal

Jiao

Wang

et al. 2021

Molecular Biology and Evolution

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Sensory systems are attractive evolutionary models to address how organisms adapt to local environments that can cause ecological speciation. However, tests of these evolutionary models have focused on visual, auditory, and olfactory senses. Here we show local adaptation of bitter taste receptor genes in two neighboring populations of a wild mammal—the blind mole rat Spalax galili—that show ecological speciation in divergent soil environments. We found that basalt-type bitter receptors showed higher response intensity and sensitivity compared with chalk-type ones using both genetic and cell-based functional analyses. Such functional changes could help animals adapted to basalt soil select plants with less bitterness from diverse local foods, whereas a weaker reception to bitter taste may allow consumption of a greater range of plants for animals inhabiting chalk soil with a scarcity of food supply. Our study shows divergent selection on food resources through local adaptation of bitter receptors, and suggests that taste plays an important yet underappreciated role in speciation.

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Section: Discussionmentioning

confidence: 99%

Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal

Jiao

Wang

et al. 2021

Molecular Biology and Evolution

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“…Leaf decoction was traditionally used as an antidiabetic therapy in Palestine and Jordan [ 359 ]. The aqueous extract of aerial parts decreased glucose levels in both diabetic and non-diabetic animals, but the effect was significant for the hyperglycemic rats only [ 358 ].…”

Section: Medicinal Plants With Potential Antidiabetic Activity In mentioning

confidence: 99%

Middle East Medicinal Plants in the Treatment of Diabetes: A Review

Abu-Odeh

Talib

2021

Molecules

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Diabetes is a global health problem, and the number of diabetic patients is in continuous rise. Conventional antidiabetic therapies are associated with high costs and limited efficiency. The use of traditional medicine and plant extracts to treat diabetes is gaining high popularity in many countries. Countries in the Middle East region have a long history of using herbal medicine to treat different diseases, including diabetes. In this review, we compiled and summarized all the in vivo and in vitro studies conducted for plants with potential antidiabetic activity in the Middle East region. Plants of the Asteraceae and Lamiaceae families are the most investigated. It is hoped that this review will contribute scientifically to evidence the ethnobotanical use of medicinal plants as antidiabetic agents. Work has to be done to define tagetes, mechanism of action and the compound responsible for activity. In addition, safety and pharmacokinetic parameters should be investigated.

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“…The collected material was dried under the shade and powdered (sieve 0.75). The methanol extract was prepared by extracting 100 g of aerial part of the plant with 500 ml of methanol by heat reflux extraction, at the temperature of 90 • C, in 2 h (Hijazi et al, 2015). The mixture was filtered through filter paper (Whatman, No.…”

Section: Plant Materials and Extract Preparationmentioning

confidence: 99%

New Insight Into the Cardioprotective Effects of Allium ursinum L. Extract Against Myocardial Ischemia-Reperfusion Injury

et al. 2021

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This study aimed to estimate the effects of increasing doses of Allium ursinum methanol extract on cardiac ischemia/reperfusion injury (I/R) with a special emphasis on the role of oxidative stress. Fifty rats were randomly divided into five groups (10 animals per group) depending on the applied treatment as follows: sham, rats who drank only tap water for 28 days and hearts were retrogradely perfused for 80 min without I/R injury, I/R, rats who drank only tap water for 28 days and hearts were exposed to ex vivo I/R injury and rats who consumed increasing doses of A. ursinum 125, 250, and 500 mg/kg for 28 days before I/R injury. Hearts from all rats were isolated and retrogradely perfused according to the Langendorff technique. Parameters of oxidative stress were spectrophotometrically measured in blood, coronary venous effluent, and heart tissue samples. Intake of wild garlic extract for 28 days significantly contributed to the recovery of cardiac function, which was reflected through preserved cardiac contractility, systolic function, and coronary vasodilatory response after ischemia. Also, wild garlic extract showed the potential to modulate the systemic redox balance and stood out as a powerful antioxidant. The highest dose led to the most efficient decrease in cardiac oxidative stress and improve recovery of myocardial function after I/R injury. We might conclude that wild garlic possesses a significant role in cardioprotection and strong antioxidant activity, which implicates the possibility of its use alone in the prevention or as adjuvant antioxidant therapy in cardiovascular diseases (CVD).

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Eryngium creticum – ethnopharmacology, phytochemistry and pharmacological activity. A review

Cited by 21 publications

References 27 publications

Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal

Local Adaptation of Bitter Taste and Ecological Speciation in a Wild Mammal

Middle East Medicinal Plants in the Treatment of Diabetes: A Review

New Insight Into the Cardioprotective Effects of Allium ursinum L. Extract Against Myocardial Ischemia-Reperfusion Injury

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