Equilibrium and kinetically trapped aggregates in polyelectrolyte–oppositely charged surfactant mixtures

Guzmán, Eduardo; Fernández‐Peña, Laura; Ortega, Francisco; Rubio, Ramón G.

doi:10.1016/j.cocis.2020.04.002

Cited by 49 publications

(53 citation statements)

References 94 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Surfactant micelles may be packed in a disordered fashion within the micellar core or instead adopt liquid-crystalline ordering [ 16 , 164 ]. More importantly, thermodynamic considerations do not fully account for the behavior of mixtures of ionic surfactants and polyelectrolytes, as, in many cases, their association leads to kinetically trapped aggregates [ 165 ]. Disadvantageously, the solubilization capacity for the hydrophobic cargo of surfactant-polyelectrolyte C3Ms is still limited.…”

Section: Biotechnological Applications Of C3msmentioning

confidence: 99%

On Complex Coacervate Core Micelles: Structure-Function Perspectives

2020

View full text Add to dashboard Cite

The co-assembly of ionic-neutral block copolymers with oppositely charged species produces nanometric colloidal complexes, known, among other names, as complex coacervates core micelles (C3Ms). C3Ms are of widespread interest in nanomedicine for controlled delivery and release, whilst research activity into other application areas, such as gelation, catalysis, nanoparticle synthesis, and sensing, is increasing. In this review, we discuss recent studies on the functional roles that C3Ms can fulfil in these and other fields, focusing on emerging structure–function relations and remaining knowledge gaps.

show abstract

Section: Biotechnological Applications Of C3msmentioning

confidence: 99%

On Complex Coacervate Core Micelles: Structure-Function Perspectives

2020

View full text Add to dashboard Cite

show abstract

“…Higher thickness cannot, however, be discounted for greater adsorption, since it was shown that adsorption of these polyelectrolytes asymptotically approaches the constant value with time and for PAA–PSS systems the increment in adsorption past those 15–20 min is not that big [ 40 ]. Another study showed that the thickness of layer-by-layer polyelectrolyte assemblies may be increased due to the presence of defects, such as pockets of electroneutral solution or coacervates [ 44 ]. We can hypothesize that the increase in thickness might be caused by the formation of defects such as these.…”

Section: Resultsmentioning

confidence: 99%

Layer-by-Layer Coating of MK-40 Heterogeneous Membrane with Polyelectrolytes Creates Samples with Low Electrical Resistance and Weak Generation of H+ and OH− Ions

et al. 2021

View full text Add to dashboard Cite

Ion exchange membranes covered with layers of polyelectrolytes of alternating charges are characterized by very high monovalent selectivity. This allows the use of such membranes for electrodialytic fractionation of multicomponent solutions. However, the very existence of the boundary at which differently charged layers come in contact can hinder a membrane’s effectiveness by limiting its ion permeability, raising levels of H+ and OH− ions (thus shifting the pH) and increasing the electrical resistance of the membrane, which leads to increased energy consumption. To test how these properties would be changed, we created cheap layer-by-layer-modified membranes based on the heterogeneous MK-40 membrane, on which we adsorbed layers of polyallylamine and sulfonated polystyrene. We created samples with 3, 4, and 5 layers of polyelectrolytes and characterized them. We showed that the application of layers did not decrease the efficiency of the membrane, since the electrical resistance of the modified samples, which increased after application of the first oppositely charged layer, declined with the application of the following layers and became comparable to that of the substrate, while their limiting current density was higher and the shift of pH of treated solution was low in magnitude and comparable with that of the substrate membrane.

show abstract

“…The assembly of LbL polyelectrolyte films needs to consider that whereas inter-polyelectrolyte complexes formed in the bulk present thermodynamic stability, the assembly process of polyelectrolyte multilayers leads to the formation of kinetically arrested supramolecular structures [ 29 , 97 , 168 , 169 ]. This may be understood considering the release of a polyelectrolyte chain from the multilayer to the solution, with such processes being associated with an important gain on the entropy of the released chain (mainly the translational and conformational one) due to the enhanced mobility of the chain in solution with respect to the situation found in the multilayer [ 170 ].…”

Section: Fabrication Of Lbl Assemblies On Colloidal Surfacesmentioning

confidence: 99%

“…The impact of the electrostatic interactions in LbL-decorated liposomes goes beyond its impact on the protection of encapsulated drugs and the integrity of the bare liposomes. The surface charge of the bare liposomes should be chosen in such a way that ensures a strong electrostatic binding between the polyelectrolyte chains and the first deposited layers [ 113 , 168 , 264 , 265 , 266 , 267 ]. This was clear from the studies by Angelini et al [ 262 ] in which an analysis of the stability against the detergent of the liposomes coated with LbL layers was performed.…”

Section: Lbl Multilayers On Liposomesmentioning

confidence: 99%

Polyelectrolyte Multilayers on Soft Colloidal Nanosurfaces: A New Life for the Layer-By-Layer Method

et al. 2021

Self Cite

View full text Add to dashboard Cite

The Layer-by-Layer (LbL) method is a well-established method for the assembly of nanomaterials with controlled structure and functionality through the alternate deposition onto a template of two mutual interacting molecules, e.g., polyelectrolytes bearing opposite charge. The current development of this methodology has allowed the fabrication of a broad range of systems by assembling different types of molecules onto substrates with different chemical nature, size, or shape, resulting in numerous applications for LbL systems. In particular, the use of soft colloidal nanosurfaces, including nanogels, vesicles, liposomes, micelles, and emulsion droplets as a template for the assembly of LbL materials has undergone a significant growth in recent years due to their potential impact on the design of platforms for the encapsulation and controlled release of active molecules. This review proposes an analysis of some of the current trends on the fabrication of LbL materials using soft colloidal nanosurfaces, including liposomes, emulsion droplets, or even cells, as templates. Furthermore, some fundamental aspects related to deposition methodologies commonly used for fabricating LbL materials on colloidal templates together with the most fundamental physicochemical aspects involved in the assembly of LbL materials will also be discussed.

show abstract

Equilibrium and kinetically trapped aggregates in polyelectrolyte–oppositely charged surfactant mixtures

Cited by 49 publications

References 94 publications

On Complex Coacervate Core Micelles: Structure-Function Perspectives

On Complex Coacervate Core Micelles: Structure-Function Perspectives

Layer-by-Layer Coating of MK-40 Heterogeneous Membrane with Polyelectrolytes Creates Samples with Low Electrical Resistance and Weak Generation of H+ and OH− Ions

Polyelectrolyte Multilayers on Soft Colloidal Nanosurfaces: A New Life for the Layer-By-Layer Method

Contact Info

Product

Resources

About