Epithelioid hemangioendothelioma of the oral cavity

Abstract

Wide local excision with long-term follow-up seems to be the treatment of choice for intraoral epithelioid hemangioendothelioma because of their unpredictable biological behaviour and recurrence potential.

Intraoral epithelioid hemangioendothelioma: A case report and review of the literature

“…A variable immunohistochemical expression to SMA for intraoral EHs has been observed previously (12,15,16) (Table 3). In the case reported here the immunoreactivity for this marker was focally, as evidenced at times immunoreactivity in myopericitics cells surrounding the neoplastic cells, showing the endothelial differentiation of these.…”

Epithelioid hemangioendothelioma of the oral cavity: a case report

“…It has a mortality rate of 13% for soft tissue lesions (9). EHE in the oral cavity is rare and only 26 cases have been reported to date (3,(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). In many of these cases, the clinical impression was that of a benign lesion including pyogenic granuloma.…”

Epithelioid hemangioendothelioma of the tongue: a report of solitary and multiple lesions in two young children

“…To the best of our knowledge, the 1-year-old child is the youngest patient with EHE reported in the literature. Although EHE can occur at any age, the tumor generally affects middle-age patients, and examples in children are distinctly rare (2,4,6,8). There have been 26 reports of oral EHE cases to date (2), the age range extending from 4 to 76 years with a mean age of 31 years.…”

“…It arises from vascular endothelial cells and can potentially occur in any organ but most commonly occurs in the deep soft tissues of the extremities as well as in the liver, lung, breast, and long bones (2). The neoplasm has peculiar histological features.…”