Epithelioid hemangioendothelioma of the tongue: a report of solitary and multiple lesions in two young children

Abstract

Case 1:A one-year-old boy with no previous medical problems presented with a history of an asymptomatic mass on the tongue. The lesion had been present for at least six months and was slowly growing. An extraoral examination showed nothing in particular. An intraoral examination showed a

Epithelioid Hemangioendothelioma– Two Rare Case Reports with Review of Literature

“…It was described as early as 1899 by Boremann, [4,5,8] and was introduced particularly in vascular tumours by Enzinger and Weiss and latter added to WHO classification in 2002 . [3,4,6,9] These HE lack consistent clinical and histological behavior with limited number of reported cases, fails to elucidate the exact biological nature of this tumour.…”

“…[3,9] The variable behavior of the neoplasm, led to its compounded terminologies such as histiocytoidhemangioma, intravascular bronchioalveol ar,malignanthemangioendothelioma, cellular angioma of infancy, angioendothelioma, angioblastoma and led to the categorization of HE as an intermediate tumors or borderline tumor. [1,2,4,6,[10][11][12] Though the concept of intermediate or borderline tumours remains complex and ill defined, it was designated to tumours with uncertain behavior. It was described as early as 1899 by Boremann, [4,5,8] and was introduced particularly in vascular tumours by Enzinger and Weiss and latter added to WHO classification in 2002 .…”

“…Hemangioendotheliomas (HE) are rare proliferative vascular neoplasms, known for its intermediate biological behavior that ranges between benign hemangiomas to malignant angiosarcomas. [1][2][3][4][5][6] Its clinical behavior and disease course remains unpredictable even amongst its histological types namely epithelioid, kaposi's and hobnail form (Dabska-retiform). Epithelioidhemangioendotheliomas (EHE) are decidedly are form of hemangioendotheliomas with biphasic histopathological components composed of characteristic short cords and nests of proliferating round to epithelioid endothelial cells as well as spindle shaped endothelial cells.…”

“…It is known to occur in any soft tissues but primarily in abdomen, liver, lung, extremities and also rarely in head and neck region. [2][3][4][5][6] Epithelioidhemangioendotheliomas are known to have…”

Hemangioendothelioma of palate: A case report with review of literature

“…[ 5 ] In oral cavity, the lesion has been encountered in gingiva, tongue, maxilla, buccal mucosa and palate. [ 6 ] Hemangioendothelioma of oral cavity is rare, with reported cases of the epithelioid variant being only around 30, while the Kaposiform variant numbers to about 14 reported cases. [ 1 ] The other variants are still fewer in number.…”