Epidemiology of severe sepsis in India

Chatterjee, Sharmila; Todi, Subhash; Sahu, Samir; Bhattacharyya, M

doi:10.1186/cc7509

Cited by 6 publications

(5 citation statements)

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“…Composite correction of metabolic parameters was achieved in about 50% of patients, but the mortality rate was high in both groups, suggesting death because of other organ involvement. Our mortality rate appeared higher than that in other centers in India, with a mortality of 60% observed in septic patients (26). Similar observations of 80% mortality have been reported in critically ill AKI patients requiring dialysis (27).…”

Section: Discussioncontrasting

confidence: 75%

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Comparing Continuous Venovenous Hemodiafiltration and Peritoneal Dialysis in Critically Ill Patients with Acute Kidney Injury: A Pilot Study

et al. 2011

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Section: Discussioncontrasting

confidence: 75%

“…Our mortality rate appeared higher than that in other centers in India, with a mortality of 60% observed in septic patients (26). Similar observations of 80% mortality have been reported in critically ill AKI patients requiring dialysis (27).…”

Section: Discussionmentioning

confidence: 36%

Comparing Continuous Venovenous Hemodiafiltration and Peritoneal Dialysis in Critically Ill Patients with Acute Kidney Injury: A Pilot Study

et al. 2011

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“…1), namely 21 male patients (56.8%) and 16 female patients (43.2%). It is following several previous studies that said that sepsis was more common in men than women [26].…”

Section: Discussionmentioning

confidence: 93%

Procalcitonin as a Marker of Sepsis Due to Bacterial Infection

Luhulima

Ronny²,

Amelia³

2022

JOCAMR

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Sepsis is one of the world's health problems that commonly cause mortality. The incidence of sepsis keeps on increasing each year. Many diagnostic parameters for sepsis caused by bacterial infection have been used but sometimes are not specific and misleading. Seeing the high number of sepsis cases needed a prompt and precise diagnostic. Aim: This study aims to evaluate the sensitivity and specificity of procalcitonin in sepsis patients caused by bacterial infection. Method: A cross-sectional study on 54 adult patients with systemic inflammatory response syndrome (12 – 75 years old) in Mitra Keluarga Bekasi Timur Hospital used patients' medical records from October to December 2016. The diagnostic test was analyzed using the receiver operating characteristic curve. Sample: In this study, there were 37 samples, 28 were sepsis patients, and 9 were non-sepsis samples. Finding: The test result of sensitivity and specificity of procalcitonin was 88,5% and 81,8%, cut off value ≥ 0,8, AUC 0,90 with p-value < 0,05. Conclusion: The conclusion is that procalcitonin can be a prompt, ideal, and efficient diagnostic marker for sepsis caused by bacterial infection with high sensitivity and specificity tests.

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“…[1][2][3] However, the reported mortality rates have varied greatly among various epidemiologic and therapeutic studies conducted in different countries and continents, ranging from 30 to 80 per cent. [1][2][3] This extreme variability has been attributed to substantial heterogeneity among septic shock patients. 1,4 Recent studies have demonstrated varying presentations of these patients.…”

mentioning

confidence: 99%

Varying Presentations and Outcomes of Septic Shock: Should Septic Shock be Stratified?

Zhu

Yin

Zhang

et al. 2017

The American Surgeon™

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Recent studies have revealed there are three presentations of septic shock in patients: refractory hypotension without hyperlactatemia, hyperlactatemia without refractory hypotension, and both refractory hypotension and hyperlactatemia. In this study, we sought to identify differences in the outcomes of septic shock patients with these three presentations. We performed a secondary analysis of a large-scale, multicenter, controlled trial. The septic shock patients were categorized into the following three groups according to the presence or absence of refractory hypotension and hyperlactatemia: a hypotension group (refractory hypotension without hyperlactatemia), a hyperlactatemia group (hyperlactatemia without refractory hypotension), and a typical group (both refractory hypotension and hyperlactatemia). The 90-day all-cause mortality was compared among these three groups. A total of 1588 septic shock patients were enrolled in the present study, including 854 (53.8%) in the hypotension group, 477 (30.0%) in the hyperlactatemia group, and 257 (16.2%) in the typical group. The 90-day all-cause mortality were 12.3 per cent for the patients in the hypotension group, 23.1 per cent for those in the hyperlactatemia group, and 31.9 per cent for those inthe typical group, these differences among the three groups were significant (Pearson's χ2 = 58.49, P < 0.001). And also, there was a significant difference between hyperlactatemia group and typical group (Pearson's χ2 = 6.77, P < 0.05). In this study, we demonstrated that the three different presentations of septic shock resulted in significantly different outcomes, suggesting that septic shock should be stratified.

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Epidemiology of severe sepsis in India

Cited by 6 publications

References 0 publications

Comparing Continuous Venovenous Hemodiafiltration and Peritoneal Dialysis in Critically Ill Patients with Acute Kidney Injury: A Pilot Study

Comparing Continuous Venovenous Hemodiafiltration and Peritoneal Dialysis in Critically Ill Patients with Acute Kidney Injury: A Pilot Study

Procalcitonin as a Marker of Sepsis Due to Bacterial Infection

Varying Presentations and Outcomes of Septic Shock: Should Septic Shock be Stratified?

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